Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 8/20 | 0.46 |
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.46 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.42 |
| ▸ | PPARG | P37231 | 6/20 | 0.37 |
| ▸ | PPARA | Q07869 | 6/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | TACR2 | P21452 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19505104 | 0.92 | TRPC5 (0.47) | TRPC5TRPC4TRPC1P2RX3PPARG | |
| SCHEMBL19505349 | 0.84 | TRPC5 (0.48) | TRPC5TRPC4TRPC1P2RX3PPARG | |
| SCHEMBL21316288 | 0.82 | TRPC5 (0.47) | TRPC5TRPC4TRPC1P2RX3PPARG | |
| SCHEMBL21499691 | 0.82 | TRPC5 (0.47) | TRPC5TRPC4TRPC1P2RX3PPARG | |
| SCHEMBL19505331 | 0.82 | P2RX3 (0.60) | TRPC5TRPC4TRPC1P2RX3 | |
| SCHEMBL24133837 | 0.82 | TRPC5 (0.57) | TRPC5TRPC4TRPC1P2RX3PPARG | |
| SCHEMBL19505055 | 0.80 | TRPC5 (0.56) | TRPC5TRPC4TRPC1P2RX3PPARG | |
| SCHEMBL21499694 | 0.79 | TRPC5 (0.43) | TRPC5TRPC4TRPC1P2RX3 | |
| SCHEMBL21499677 | 0.79 | TRPC5 (0.51) | TRPC5TRPC4TRPC1P2RX3KCNH2 | |
| SCHEMBL21499669 | 0.79 | TRPC5 (0.49) | TRPC5TRPC4TRPC1P2RX3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-09-20 | — | — | EP | disclosed |