Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MYOC | Q99972 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12477112 | 0.92 | HTR2A (0.57) | HTR2AALDH1A1MAPK1L3MBTL1LTA4H | |
| SCHEMBL20164115 | 0.89 | HTR2A (0.56) | HTR2AALDH1A1MAPK1L3MBTL1LTA4H | |
| SCHEMBL20164114 | 0.89 | HTR2A (0.56) | HTR2AALDH1A1MAPK1L3MBTL1LTA4H | |
| SCHEMBL17300183 | 0.89 | HTR2A (0.62) | HTR2AALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL15676012 | 0.89 | HTR2A (0.56) | HTR2AALDH1A1MAPK1L3MBTL1LTA4H | |
| SCHEMBL18975354 | 0.86 | HTR2A (0.67) | HTR2AALDH1A1MAPK1L3MBTL1LTA4H | |
| SCHEMBL19432446 | 0.86 | HTR2A (0.67) | HTR2AALDH1A1MAPK1L3MBTL1LTA4H | |
| SCHEMBL19209358 | 0.86 | HTR2A (0.55) | HTR2AALDH1A1MAPK1L3MBTL1LTA4H | |
| SCHEMBL15810831 | 0.85 | LTA4H (0.57) | HTR2AALDH1A1MAPK1L3MBTL1LTA4H | |
| SCHEMBL16949548 | 0.85 | HTR2A (0.52) | HTR2AALDH1A1MAPK1L3MBTL1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170266308-A1 | SMALL MOLECULE CONJUGATES SPECIFICALLY ACTIVATED IN TUMOR MICROENVIROMENT FOR TARGETING AND USE THEREOF | YAFEI SHANGHAI BIOLOG MEDICINE SCIENCE & TECHNOLOGY CO. LTD. (CN) | 2017-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170266308-A1 | SMALL MOLECULE CONJUGATES SPECIFICALLY ACTIVATED IN TUMOR MICROENVIROMENT FOR TARGETING AND USE THEREOF | CD4, MET, TNFSF10 | HTR2A 4302/4885ALDH1A1 3614/4885MAPK1 2208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.