Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NR1D1 | P20393 | 7/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9231883 | 0.79 | MAPT (0.47) | MAPTKDM4EHTTALDH1A1L3MBTL1 | |
| SCHEMBL28991326 | 0.77 | MAPT (0.46) | MAPTKDM4EHTTALDH1A1L3MBTL1 | |
| SCHEMBL31467963 | 0.76 | — | — | |
| SCHEMBL7753003 | 0.76 | MAPT (0.53) | MAPTKDM4EHTTALDH1A1L3MBTL1 | |
| SCHEMBL4880954 | 0.76 | MAPT (0.53) | MAPTKDM4EHTTALDH1A1L3MBTL1 | |
| SCHEMBL7048967 | 0.76 | KMT2A (0.54) | MAPTKDM4EHTTALDH1A1L3MBTL1 | |
| SCHEMBL960965 | 0.76 | MAPT (0.53) | MAPTKDM4EHTTALDH1A1L3MBTL1 | |
| SCHEMBL10160727 | 0.76 | KMT2A (0.54) | MAPTKDM4EHTTALDH1A1L3MBTL1 | |
| SCHEMBL6261093 | 0.73 | MAPT (0.52) | MAPTKDM4EHTTALDH1A1L3MBTL1 | |
| SCHEMBL8423313 | 0.73 | MAPT (0.50) | MAPTKDM4EHTTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331532-A1 | THIENYLAMINO PYRIMIDINES FOR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010025851-A1 | THIENYLAMINO PYRIMIDINES FOR USE AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | disclosed |