Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | NR1D1 | P20393 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27481963 | 0.84 | MAPT (0.50) | MAPTALDH1A1KDM4EHTTL3MBTL1 | |
| SCHEMBL7048967 | 0.79 | KMT2A (0.54) | MAPTALDH1A1KDM4EHTTL3MBTL1 | |
| SCHEMBL10160727 | 0.79 | KMT2A (0.54) | MAPTALDH1A1KDM4EHTTL3MBTL1 | |
| SCHEMBL4880954 | 0.79 | MAPT (0.53) | MAPTALDH1A1KDM4EHTTL3MBTL1 | |
| SCHEMBL960965 | 0.79 | MAPT (0.53) | MAPTALDH1A1KDM4EHTTL3MBTL1 | |
| SCHEMBL11537633 | 0.77 | KMT2A (0.49) | MAPTALDH1A1KDM4EHTTL3MBTL1 | |
| SCHEMBL6261093 | 0.77 | MAPT (0.52) | MAPTALDH1A1KDM4EHTTL3MBTL1 | |
| SCHEMBL8423313 | 0.76 | MAPT (0.50) | MAPTALDH1A1KDM4EHTTL3MBTL1 | |
| SCHEMBL20590054 | 0.76 | MAPT (0.50) | MAPTALDH1A1KDM4EHTTL3MBTL1 | |
| SCHEMBL1937601 | 0.76 | MAPT (0.50) | MAPTALDH1A1KDM4EHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119060054-A | Nitroaromatic ring substituted imidazopyrazine compound and preparation method and application thereof | 南京中医药大学 | 2024-12-03 | — | — | CN | disclosed |
| CN-118475563-A | Cyanine-trehalose compound, preparation method and application thereof | 宁波康柏睿格医药科技有限公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-113980075-B | Fluodrone derivative and application thereof | 聊城大学 | 2024-06-04 | — | — | CN | disclosed |
| WO-2023216992-A1 | CYANINE-TREHALOSE COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | 杭州康柏睿格医药科技有限公司 | 2023-11-16 | — | — | WO | disclosed |
| US-20230167142-A1 | METHODS FOR THE MONO-AMIDATION OF PHOSPHATES AND PHOSPHONATES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2023-06-01 | — | — | US | disclosed |
| US-20220089620-A1 | INHIBITORS OF THE ENZYME ENOLASE FOR PRECISION ONCOLOGY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2022-03-24 | — | — | US | disclosed |
| CN-113980005-A | Tegafur derivatives and use thereof | 聊城大学 | 2022-01-28 | — | — | CN | disclosed |
| CN-113980075-A | Fluoroteflon derivative and application thereof | 聊城大学 | 2022-01-28 | — | — | CN | disclosed |
| WO-2021202886-A1 | METHODS FOR THE MONO-AMIDATION OF PHOSPHATES AND PHOSPHONATES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-10-07 | — | — | WO | disclosed |
| WO-2020154742-A1 | INHIBITORS OF THE ENZYME ENOLASE FOR PRECISION ONCOLOGY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-07-30 | — | — | WO | disclosed |
| EP-0769015-B1 | PHOSPHONIC ACID COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-03-14 | — | — | EP | disclosed |
| US-5874472-A | Aminoacid derivatives as no synthase inhibitors | GLAXO WELLCOME INC. (US) | 1999-02-23 | — | — | US | disclosed |
| EP-0705257-B1 | AMINOACID DERIVATIVES AS NO SYNTHASE INHIBITORS | WELLCOME FOUND (GB) | 1998-03-11 | — | — | EP | disclosed |
| US-5716944-A | USEFUL AS PROPHYLACTIC AND THERAPEUTIC AGENTS OF VARIOUS METABOLIC BONE DISEASES SUCH AS OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0769015-A1 | PHOSPHONIC ACID COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-04-23 | — | — | EP | disclosed |
| EP-0705257-A1 | AMINOACID DERIVATIVES AS NO SYNTHASE INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-04-10 | — | — | EP | disclosed |
| WO-1996001267-A1 | PHOSPHONIC ACID COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-18 | — | — | WO | disclosed |
| WO-1995000505-A1 | AMINOACID DERIVATIVES AS NO SYNTHASE INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220089620-A1 | INHIBITORS OF THE ENZYME ENOLASE FOR PRECISION ONCOLOGY | ENO1, SERPINB1, ENPEP | MAPT 1234/4885ALDH1A1 921/4885KDM4E 1752/4885 |
| US-20230167142-A1 | METHODS FOR THE MONO-AMIDATION OF PHOSPHATES AND PHOSPHONATES | PHPT1, PPIP5K2, PNP | MAPT 3158/4885ALDH1A1 4707/4885KDM4E 3560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.