Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 3/20 | 0.66 |
| ▸ | FLT3 | P36888 | 7/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.51 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936754 | 0.86 | ULK1 (0.60) | — | |
| SCHEMBL1937628 | 0.84 | ULK1 (0.60) | PRKCQFLT3CHEK1PTK2SYK | |
| SCHEMBL1937645 | 0.82 | PRKCQ (0.65) | PRKCQFLT3CHEK1PTK2EGFR | |
| SCHEMBL1916640 | 0.80 | PRKCQ (0.79) | PRKCQFLT3CHEK1PTK2SYK | |
| SCHEMBL1917739 | 0.80 | PRKCQ (1.00) | PRKCQFLT3CHEK1 | |
| SCHEMBL1916646 | 0.79 | PRKCQ (0.78) | PRKCQFLT3CHEK1PTK2 | |
| SCHEMBL1917067 | 0.76 | CHEK1 (0.65) | PRKCQFLT3CHEK1PTK2SYK | |
| SCHEMBL17545033 | 0.76 | ULK1 (0.73) | PRKCQFLT3CHEK1 | |
| SCHEMBL1916705 | 0.75 | CHEK1 (0.72) | PRKCQFLT3CHEK1PTK2SYK | |
| SCHEMBL3283696 | 0.74 | PRKCQ (0.78) | PRKCQFLT3CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331533-A1 | HETEROCYCLICALLY SUBSTITUTED ANILINOPYRIMIDINES AS FUNGICIDES | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010025850-A1 | HETEROCYCLICALLY SUBSTITUTED ANILINOPYRIMIDINES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | disclosed |