Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 10/20 | 0.50 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.46 |
| ▸ | STARD10 | Q9Y365 | 1/20 | 0.46 |
| ▸ | IDH1 | O75874 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 3/20 | 0.44 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19377339 | 1.00 | GHSR (0.50) | GHSRPCTPSTARD10IDH1NAMPT | |
| SCHEMBL19377310 | 0.92 | GHSR (0.48) | GHSRPCTPSTARD10IDH1NAMPT | |
| SCHEMBL19377314 | 0.92 | GHSR (0.48) | GHSRPCTPSTARD10IDH1NAMPT | |
| SCHEMBL19377392 | 0.92 | GHSR (0.53) | GHSRPCTPSTARD10IDH1NAMPT | |
| SCHEMBL19377394 | 0.92 | GHSR (0.53) | GHSRPCTPSTARD10IDH1NAMPT | |
| SCHEMBL19377130 | 0.90 | GAA (0.54) | GHSRPCTPSTARD10IDH1NAMPT | |
| SCHEMBL19377446 | 0.90 | GPR27 (0.55) | GHSRIDH1GPR27MEN1MAPT | |
| SCHEMBL19377444 | 0.90 | GPR27 (0.55) | GHSRIDH1GPR27MEN1MAPT | |
| SCHEMBL19377487 | 0.89 | MEN1 (0.52) | GHSRPCTPSTARD10IDH1NAMPT | |
| SCHEMBL19377486 | 0.89 | MEN1 (0.52) | GHSRPCTPSTARD10IDH1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170275301-A1 | Benzenesulfonyl-Asymmetric Ureas and Medical Uses Thereof | HELSINN HEALTHCARE SA (CH) | 2017-09-28 | — | — | US | claimed |
| US-20170275301-A1 | Benzenesulfonyl-Asymmetric Ureas and Medical Uses Thereof | HELSINN HEALTHCARE SA (CH) | 2017-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170275301-A1 | Benzenesulfonyl-Asymmetric Ureas and Medical Uses Thereof | UTS2R, GHSR, GRPR | GHSR 2/4885PCTP 2942/4885STARD10 3766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.