SCHEMBL193780

SCHEMBL193780

O=Cc1ccn[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL30730045 0.93 HCAR2 (0.40)
SCHEMBL543822 0.74
SCHEMBL19361929 0.74
SCHEMBL28848599 0.74 COMT (0.38)
SCHEMBL2638363 0.72
SCHEMBL30228233 0.70
SCHEMBL19361932 0.70
SCHEMBL20517721 0.69 KMT2A (0.49)
SCHEMBL24654635 0.69
SCHEMBL22482851 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 787 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4522606-A1 INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS AND METAPNEUMOVIRUS Merck Sharp & Dohme LLC (US) 2025-03-19 EP claimed
EP-4359368-A1 COMBINATION OF A PYRAZOLE AND A THIOPHOSPHORIC TRIAMIDE WockLab GmbH & Co. KG (DE) 2024-05-01 EP claimed
WO-2023220223-A1 INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS AND METAPNEUMOVIRUS MERCK SHARP & DOHME LLC (US) 2023-11-16 WO claimed
WO-2022268777-A1 COMBINATION OF A PYRAZOLE AND A THIOPHOSPHORIC TRIAMIDE WOCKLAB GMBH & CO. KG (DE) 2022-12-29 WO claimed
CN-111620878-A Pyrrolopyrimidine derivatives as protein kinase inhibitors and application thereof 中国药科大学 2020-09-04 CN claimed
CN-107298682-B A kind of synthetic method of 4,5,6,7- tetrahydro-pyrazole simultaneously [1,5-A] pyrazine -2- Ethyl formate 天津药明康德新药开发有限公司 2019-03-01 CN claimed
CN-107298682-A A kind of synthetic method of the 4,5,6,7 tetrahydro-pyrazoles simultaneously Ethyl formate of [1,5 A] pyrazine 2 天津药明康德新药开发有限公司 2017-10-27 CN claimed
CN-107108600-A It is used as the heteroarylalkylenyl aryl sultam derivative of RORc conditioning agents 豪夫迈·罗氏有限公司 2017-08-29 CN claimed
CN-106928143-A Preparation method of 2- (4-bromo-1-methyl-1H-pyrazol-5-yl) ethylamine 北京六合宁远科技有限公司 2017-07-07 CN claimed
CN-105944509-A Method for capturing sulfur dioxide by using aldehyde-group-containing anion functionalized ionic liquid 河南师范大学 2016-09-21 CN claimed
CN-102791714-A N-(imidazopyrimidin-7-yl)-heteroarylamide derivatives and their use as PDE10A inhibitors HOFFMANN LA ROCHE 2012-11-21 CN claimed
CN-102405036-A Keratin dyeing compositions comprising free radical scavengers and uses thereof PROCTER & GAMBLE 2012-04-04 CN claimed
CN-100448425-C Diaminopyrazole-containing dyeing composition for keratin fibers, dyeing method, novel diaminopyrazoles and process for preparing same OREAL (FR) 2009-01-07 CN claimed
CN-1976938-A Thienopyrazole derivatives having PDE7 inhibitory activity ASUBIO PHARMA CO LTD (JP) 2007-06-06 CN claimed
CN-1968922-A Factor XA inhibitors MILLENNIUM PHARM INC (US) 2007-05-23 CN claimed
CN-1324608-A Keratin-fiber oxidation dyeing composition and method of dyeing using said composition OREAL (FR) 2001-12-05 CN claimed
CN-1189772-A Diaminopyrazole-containing compositions for colouring keratin fibres, colouring process, novel diaminopyrazoles and method for their prepn. OREAL (FR) 1998-08-05 CN claimed
US-5017212-A For rice paddies TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-05-21 US claimed
CN-1035828-A Benzo benzodioxole derivatives and preparation method thereof TANABE SEIYAKU CO (JP) 1989-09-27 CN claimed
EP-0329326-A1 Benzodioxole derivatives and processes for preparing the same TANABE SEIYAKU CO., LTD. (JP) 1989-08-23 EP claimed