Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 8/20 | 0.71 |
| ▸ | FAAH | O00519 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13695959 | 1.00 | MGLL (0.71) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL9917596 | 1.00 | MGLL (0.71) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL12286751 | 1.00 | MGLL (0.71) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL13139285 | 0.96 | MGLL (0.64) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL21441690 | 0.92 | MGLL (0.59) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL25721630 | 0.91 | MGLL (0.59) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL27255957 | 0.89 | MGLL (0.56) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL30009171 | 0.84 | MGLL (1.00) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL9643398 | 0.84 | MGLL (1.00) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL15483488 | 0.84 | MGLL (1.00) | MGLLFAAHALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753431-B2 | Compounds comprising cleavable linker and uses thereof | INTOCELL, INC. (KR) | 2023-09-12 | — | — | US | disclosed |
| US-20230190939-A1 | ANTIBODY DRUG CONJUGATES COMPRISING TOXINS WITH POLAR GROUPS AND USES THEREOF | INTOCELL, INC. (KR) | 2023-06-22 | — | — | US | disclosed |
| EP-2400992-B1 | METHODS AND COMPOSITIONS FOR PROTEIN LABELLING | GENENTECH INC (US) | 2015-07-22 | — | — | EP | disclosed |
| US-8865122-B2 | Methods and compositions for protein labelling | GENENTECH, INC. (US) | 2014-10-21 | — | — | US | disclosed |
| US-20130216475-A1 | METHODS AND COMPOSITIONS FOR PROTEIN LABELLING | GENENTECH, INC. (US) | 2013-08-22 | — | — | US | disclosed |
| US-8435488-B2 | Methods and compositions for protein labelling | GENENTECH, INC. (US) | 2013-05-07 | — | — | US | disclosed |
| EP-2400992-A1 | METHODS AND COMPOSITIONS FOR PROTEIN LABELLING | Genentech, Inc. (US) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010099273-A1 | METHODS AND COMPOSITIONS FOR PROTEIN LABELLING | GENENTECH, INC. (US) | 2010-09-02 | — | — | WO | disclosed |
| US-20100221176-A1 | METHODS AND COMPOSITIONS FOR PROTEIN LABELLING | GENENTECH, INC. | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230190939-A1 | ANTIBODY DRUG CONJUGATES COMPRISING TOXINS WITH POLAR GROUPS AND USES THEREOF | CD47, ENPP2, CD2 | MGLL 3709/4885FAAH 2822/4885ALDH1A1 4468/4885 |
| US-20100221176-A1 | METHODS AND COMPOSITIONS FOR PROTEIN LABELLING | RAB5IF, RPS27A, PSMA6 | MGLL 1839/4885FAAH 2095/4885ALDH1A1 4242/4885 |
| US-11753431-B2 | Compounds comprising cleavable linker and uses thereof | VIP, ANTXR2, TNFRSF9 | MGLL 4246/4885FAAH 2362/4885ALDH1A1 4822/4885 |
| US-20130216475-A1 | METHODS AND COMPOSITIONS FOR PROTEIN LABELLING | RAB5IF, RPS27A, PSMA6 | MGLL 1839/4885FAAH 2095/4885ALDH1A1 4242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.