Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 0.73 |
| ▸ | CA12 | O43570 | 12/20 | 0.73 |
| ▸ | CA1 | P00915 | 12/20 | 0.73 |
| ▸ | CA9 | Q16790 | 12/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | CA5A | P35218 | 1/20 | 0.65 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetylsulfanilamide SCHEMBL359721 | 0.86 | CA1 (1.00) | CA2CA12CA1CA9KMT2A | |
| SCHEMBL13784930 | 0.85 | CA2 (0.76) | CA2CA12CA1CA9KMT2A | |
| SCHEMBL20822237 | 0.85 | CA2 (0.76) | CA2CA12CA1CA9KMT2A | |
| Acetylsulfanilamide SCHEMBL28550936 | 0.84 | CA1 (0.96) | CA2CA12CA1CA9KMT2A | |
| Acetylsulfanilamide SCHEMBL8190989 | 0.84 | CA1 (0.96) | CA2CA12CA1CA9KMT2A | |
| Acetylsulfanilamide SCHEMBL8043497 | 0.84 | CA1 (0.96) | CA2CA12CA1CA9KMT2A | |
| SCHEMBL20822191 | 0.84 | CA2 (0.72) | CA2CA12CA1CA9KMT2A | |
| Acetylsulfanilamide SCHEMBL17360801 | 0.83 | CA1 (0.86) | CA2CA12CA1CA9KMT2A | |
| SCHEMBL7495027 | 0.83 | CA1 (0.69) | CA2CA12CA1CA9MAPT | |
| SCHEMBL671546 | 0.82 | CA2 (1.00) | CA2CA12CA1CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017161170-A1 | CARBONIC ANHYDRASE IX TARGETING AGENTS AND METHODS | PURDUE RESEARCH FOUNDATION (US) | 2017-09-21 | — | — | WO | disclosed |