Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 14/20 | 0.96 |
| ▸ | CA2 | P00918 | 14/20 | 0.96 |
| ▸ | CA12 | O43570 | 9/20 | 0.96 |
| ▸ | CA9 | Q16790 | 9/20 | 0.96 |
| ▸ | IDO1 | P14902 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | PLK1 | P53350 | 1/20 | 0.68 |
| ▸ | CA7 | P43166 | 2/20 | 0.67 |
| ▸ | CA4 | P22748 | 1/20 | 0.67 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.64 |
| ▸ | MMP1 | P03956 | 1/20 | 0.62 |
| ▸ | MMP2 | P08253 | 1/20 | 0.62 |
| ▸ | MMP9 | P14780 | 1/20 | 0.62 |
| ▸ | MMP8 | P22894 | 1/20 | 0.62 |
| ▸ | MMP13 | P45452 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetylsulfanilamide SCHEMBL359721 | 0.98 | CA1 (1.00) | CA1CA2CA12CA9IDO1 | |
| Acetylsulfanilamide SCHEMBL28550936 | 0.96 | CA1 (0.96) | CA1CA2CA12CA9IDO1 | |
| Acetylsulfanilamide SCHEMBL8190989 | 0.96 | CA1 (0.96) | CA1CA2CA12CA9IDO1 | |
| Acetylsulfanilamide SCHEMBL17360801 | 0.91 | CA1 (0.86) | CA1CA2CA12CA9IDO1 | |
| Acetylsulfanilamide SCHEMBL7429740 | 0.85 | CA1 (0.76) | CA1CA2CA12CA9IDO1 | |
| Sulfanilamide SCHEMBL11380883 | 0.84 | CA1 (0.73) | CA1CA2CA12CA9IDO1 | |
| SCHEMBL19379986 | 0.84 | CA2 (0.73) | CA1CA2CA12CA9KMT2A | |
| SCHEMBL27291831 | 0.83 | CA1 (0.73) | CA1CA2CA12CA9KMT2A | |
| SCHEMBL28226036 | 0.82 | CA1 (0.67) | CA1CA2CA12CA9KMT2A | |
| Acedapsone SCHEMBL152710 | 0.82 | PKM (0.85) | CA1CA2CA12CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118203103-A | Natural sweetness enhancer composition | 伊比西(北京)植物药物技术有限公司 | 2024-06-18 | — | — | CN | disclosed |
| US-6030976-A | SELECTIVE AFFINITY TO 5HT-6 RECEPTORS; CENTRAL NERVOUS SYSTEM DISORDERS; ALZHEIMER'S DISEASE, PSYCHOSES, SCHIZOPHRENIA, MANIC DEPRESSIONS, MEMORY DISORDERS, PARKINSON'S DISEASE, AMYOTROPHIC LATERAL SCLEROSIS AND HUNTINGTON'S DISEASE | HOFFMAN-LA ROCHE INC. (US) | 2000-02-29 | — | — | US | disclosed |
| US-5998665-A | THERAPY FOR NERVOUS SYSTEM DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1999-12-07 | — | — | US | disclosed |
| US-5939451-A | INDOL-4-YL-BENZENESULFONAMIDES AS ACTIVE MATERIAL TREATING MALARIA, BACTERIAL INFECTION, NEUROLOGICAL DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1999-08-17 | — | — | US | disclosed |
| US-5932599-A | 4-AMINO-N-(PYRIDINYL-4-YL)-BENZENESULFONAMIDES AS ACTIVE MATERIAL TREATING MALARIA, BACTERIAL INFECTION, NEUROLOGICAL DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1999-08-03 | — | — | US | disclosed |