Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 17/20 | 0.52 |
| ▸ | CA1 | P00915 | 16/20 | 0.52 |
| ▸ | CA4 | P22748 | 12/20 | 0.52 |
| ▸ | CA9 | Q16790 | 12/20 | 0.52 |
| ▸ | CA12 | O43570 | 11/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 11/20 | 0.52 |
| ▸ | CA5A | P35218 | 10/20 | 0.52 |
| ▸ | CA7 | P43166 | 10/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 10/20 | 0.52 |
| ▸ | CA3 | P07451 | 9/20 | 0.52 |
| ▸ | CA6 | P23280 | 9/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 9/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31098806 | 0.98 | KMT2A (0.58) | KMT2ACA2CA1CA4CA9 | |
| SCHEMBL19382918 | 0.98 | KMT2A (0.58) | KMT2ACA2CA1CA4CA9 | |
| SCHEMBL14315055 | 0.79 | CA2 (0.53) | KMT2ACA2CA1CA4CA9 | |
| SCHEMBL8046428 | 0.78 | KMT2A (0.91) | KMT2A | |
| SCHEMBL17599913 | 0.78 | KMT2A (0.91) | KMT2A | |
| SCHEMBL31652507 | 0.77 | KMT2A (0.89) | KMT2A | |
| SCHEMBL4673462 | 0.77 | KMT2A (0.73) | KMT2A | |
| SCHEMBL19359112 | 0.77 | CA1 (0.83) | CA2CA1CA4CA9CA12 | |
| SCHEMBL5550978 | 0.77 | KMT2A (0.76) | KMT2A | |
| SCHEMBL14086099 | 0.76 | KMT2A (0.81) | KMT2ACA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017161195-A1 | CA IX-TARGET NIR DYES AND THEIR USES | On Target Laboratories, LLC (US) | 2017-09-21 | — | — | WO | disclosed |