Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12416579 | 0.91 | TDP1 (0.43) | KDM4EALDH1A1SMN1; SMN2USP2TDP1 | |
| SCHEMBL7524394 | 0.89 | KDM4E (0.55) | KDM4EALDH1A1SMN1; SMN2USP2TDP1 | |
| SCHEMBL29550232 | 0.89 | KDM4E (0.55) | KDM4EALDH1A1SMN1; SMN2USP2TDP1 | |
| SCHEMBL2787881 | 0.87 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2USP2TDP1 | |
| SCHEMBL1938347 | 0.86 | KDM4E (0.43) | KDM4EALDH1A1SMN1; SMN2USP2TDP1 | |
| SCHEMBL25123525 | 0.86 | ALDH1A1 (0.60) | KDM4EALDH1A1SMN1; SMN2USP2TDP1 | |
| SCHEMBL25796435 | 0.86 | ALDH1A1 (0.60) | KDM4EALDH1A1SMN1; SMN2USP2TDP1 | |
| SCHEMBL1938350 | 0.83 | THRB (0.46) | KDM4EALDH1A1SMN1; SMN2USP2TDP1 | |
| SCHEMBL29315511 | 0.83 | KDM4E (0.54) | KDM4EALDH1A1SMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL10580556 | 0.82 | THRB (0.50) | KDM4EALDH1A1SMN1; SMN2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331046-A2 | DENTAL COMPOSITION COMPRISING BIPHENYL DI(METH)ACRYLATE MONOMER | 3M Innovative Properties Company (US) | 2011-06-15 | — | — | EP | disclosed |