Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125445 | 0.83 | MEN1 (0.39) | TSHRMEN1KMT2ACYP2C19 | |
| SCHEMBL464421 | 0.83 | MEN1 (0.39) | TSHRMEN1KMT2ACYP2C19 | |
| SCHEMBL19784271 | 0.83 | MEN1 (0.39) | TSHRMEN1KMT2ACYP2C19 | |
| SCHEMBL25954641 | 0.83 | MEN1 (0.39) | TSHRMEN1KMT2ACYP2C19 | |
| SCHEMBL14416580 | 0.78 | MEN1 (0.35) | TSHRMEN1KMT2ACYP2C19 | |
| SCHEMBL14272007 | 0.78 | MEN1 (0.35) | TSHRMEN1KMT2ACYP2C19 | |
| SCHEMBL12230288 | 0.78 | MEN1 (0.35) | TSHRMEN1KMT2ACYP2C19 | |
| SCHEMBL13297303 | 0.78 | MEN1 (0.35) | TSHRMEN1KMT2ACYP2C19 | |
| SCHEMBL19772551 | 0.78 | MEN1 (0.35) | TSHRMEN1KMT2ACYP2C19 | |
| SCHEMBL12230287 | 0.78 | MEN1 (0.35) | TSHRMEN1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130059816-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF AUTOIMMUNE AND OTHER DISEASE | CERULEAN PHARMA INC. (US) | 2013-03-07 | — | — | US | disclosed |
| US-20120058971-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY | CERULEAN PHARMA INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20110237540-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY | CERULEAN PHARMA INC. | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058971-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY | SDCBP, DDOST, DSC1 | TSHR 4340/4885MEN1 3636/4885KMT2A 4479/4885 |
| US-20110237540-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY | SDCBP, DDOST, DSC1 | TSHR 4340/4885MEN1 3636/4885KMT2A 4479/4885 |
| US-20130059816-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF AUTOIMMUNE AND OTHER DISEASE | PHOSPHO1, SGMS1, SGMS2 | TSHR 2636/4885MEN1 1397/4885KMT2A 3696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.