SCHEMBL193848

SCHEMBL193848

C=CC(=O)OCCOc1ccc(C(CC)c2ccc(OCCOC(=O)C=C)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.66
TSHR P16473 4/20 0.46
HPGD P15428 1/20 0.46
ALDH1A1 P00352 4/20 0.42
TP53 P04637 2/20 0.42
HIF1A Q16665 2/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
FFAR1 O14842 1/20 0.40
FAAH O00519 1/20 0.40
ACACB O00763 1/20 0.40
L3MBTL1 Q9Y468 3/20 0.39
POLB P06746 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3886442 0.95 THRB (0.59) THRBTSHRHPGDALDH1A1TP53
SCHEMBL8031168 0.93 THRB (0.56) THRBTSHRHPGDALDH1A1TDP1
SCHEMBL5550470 0.90 THRB (0.54) THRBTSHRHPGDALDH1A1TP53
SCHEMBL26981909 0.88 THRB (0.58) THRBTSHRHPGDALDH1A1TDP1
SCHEMBL25784262 0.87 THRB (0.60) THRBTSHRHPGDALDH1A1TDP1
SCHEMBL28687260 0.87 THRB (0.48) THRBTSHRHPGDALDH1A1TP53
SCHEMBL8844434 0.85 THRB (0.65) THRBTSHRHPGDALDH1A1TP53
SCHEMBL22710564 0.85 THRB (0.69) THRBTSHRHPGDALDH1A1TP53
SCHEMBL13144357 0.85 THRB (0.69) THRBTSHRHPGDALDH1A1TP53
SCHEMBL9489063 0.84 THRB (0.83) THRBTSHRHPGDALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1058 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10889732-B2 Monochromatic actinic radiation curable coatings for optical fiber DSM IP ASSETS B.V. (NL) 2021-01-12 US claimed
US-10398805-B2 Light adjustable intraocular lenses using upconverting nanoparticles and near infrared (NIR) light CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2019-09-03 US claimed
US-20180177922-A1 LIGHT ADJUSTABLE INTRAOCULAR LENSES USING UPCONVERTING NANOPARTICLES AND NEAR INFRARED (NIR) LIGHT CALIFORNIA INSTITUTE OF TECHNOLOGY 2018-06-28 US claimed
EP-2630163-B1 ULTRA FAST PROCESS FOR THE PREPARATION OF POLYMER NANOPARTICLES MAX PLANCK GESELLSCHAFT (DE) 2018-05-16 EP claimed
US-8921444-B2 Process for the modification of polymers, in particular polymer nanoparticles MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) 2014-12-30 US claimed
US-8921442-B2 Ultra fast process for the preparation of polymer nanoparticles MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E. V. (DE) 2014-12-30 US claimed
US-20130261211-A1 PROCESS FOR THE MODIFICATION OF POLYMERS, IN PARTICULAR POLYMER NANOPARTICLES MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) 2013-10-03 US claimed
US-20130261210-A1 ULTRA FAST PROCESS FOR THE PREPARATION OF POLYMER NANOPARTICLES MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) 2013-10-03 US claimed
EP-2630164-A1 PROCESS FOR THE MODIFICATION OF POLYMERS, IN PARTICULAR POLYMER NANOPARTICLES Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2013-08-28 EP claimed
EP-2630163-A1 ULTRA FAST PROCESS FOR THE PREPARATION OF POLYMER NANOPARTICLES Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2013-08-28 EP claimed
EP-1617936-A1 COMPOSITE MATERIALS COMPRISING SUPPORTED POROUS GELS McMASTER UNIVERSITY (CA) 2006-01-25 EP claimed
WO-2005021634-A2 ULTRAVIOLET LIGHT CURING COMPOSITIONS FOR COMPOSITE REPAIR TEXAS RESEARCH INTERNATIONAL, INC. (US) 2005-03-10 WO claimed
US-20050032931-A1 Ink jet recording medium CIBA SPECIALTY CHEMICALS CORP. 2005-02-10 US claimed
WO-2005011993-A2 INK JET RECORDING MEDIUM CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-02-10 WO claimed
US-20050020729-A1 Poly(vinylalcohol)-co-poly(vinylamine)polymers comprising functional moieties CIBA SPECIALTY CHEMICALS CORP. 2005-01-27 US claimed
US-20040235977-A1 Ultraviolet light curing compositions for composite repair TEXAS RESEARCH INTERNATIONAL, INC. 2004-11-25 US claimed
EP-1456250-A2 POLY(VINYLALCOHOL),CO-POLY(VINYLAMINE) POLYMERS COMPRISING FUNCTIOAL MOIETIES Ciba SC Holding AG (CH) 2004-09-15 EP claimed
WO-2004073843-A1 COMPOSITE MATERIALS COMPRISING SUPPORTED POROUS GELS MCMASTER UNIVERSITY (CA) 2004-09-02 WO claimed
WO-2003054030-A2 POLY(VINYLALCOHOL)-CO-POLY(VINYLAMINE) POLYMERS COMPRISING FUNCTIOAL MOIETIES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-07-03 WO claimed
US-5369140-A Hydroxyphenyl triazines, clear topcoats CIBA-GEIGY CORPORATION (US) 1994-11-29 US claimed