SCHEMBL25784262

SCHEMBL25784262

C=CC(=O)OCCOc1ccc(C(C)CC)cc1

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.60
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
ALDH1A1 P00352 3/20 0.55
TSHR P16473 2/20 0.55
LMNA P02545 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
HPGD P15428 1/20 0.45
HSP90AA1 P07900 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ACACB O00763 2/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25784271 0.93 MEN1 (0.59) THRBMEN1KMT2ATDP1ALDH1A1
SCHEMBL15958509 0.92 THRB (0.51) THRBMEN1KMT2ATDP1ALDH1A1
SCHEMBL193848 0.87 THRB (0.66) THRBMEN1KMT2ATDP1ALDH1A1
SCHEMBL8844434 0.87 THRB (0.65) THRBMEN1KMT2ATDP1ALDH1A1
SCHEMBL8827921 0.86 THRB (0.57) THRBMEN1KMT2ATDP1ALDH1A1
SCHEMBL10182899 0.84 TSHR (0.44) THRBMEN1KMT2ATDP1ALDH1A1
SCHEMBL13144357 0.84 THRB (0.69) THRBMEN1KMT2ATDP1ALDH1A1
SCHEMBL22710564 0.84 THRB (0.69) THRBMEN1KMT2ATDP1ALDH1A1
SCHEMBL14565941 0.83 THRB (0.42) THRBMEN1KMT2ATDP1ALDH1A1
SCHEMBL9489063 0.83 THRB (0.83) THRBMEN1KMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230217718-A1 METHOD FOR PRODUCING LIGHT-EMITTING ELEMENTS CENTRAL GLASS COMPANY, LIMITED (JP) 2023-07-06 US disclosed