Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 16/20 | 0.53 |
| ▸ | STK4 | Q13043 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18949455 | 0.86 | EGFR (0.64) | EGFRERBB2STK4 | |
| SCHEMBL18933435 | 0.86 | EGFR (0.50) | EGFRERBB2STK4 | |
| SCHEMBL19389849 | 0.81 | EGFR (0.56) | EGFRERBB2 | |
| SCHEMBL18933398 | 0.80 | EGFR (0.61) | EGFRERBB2 | |
| SCHEMBL19389827 | 0.80 | EGFR (0.64) | EGFRERBB2STK4 | |
| SCHEMBL18933474 | 0.80 | EGFR (0.64) | EGFRERBB2STK4 | |
| SCHEMBL18949445 | 0.80 | EGFR (0.64) | EGFRERBB2STK4 | |
| SCHEMBL18949458 | 0.80 | EGFR (0.56) | EGFRERBB2 | |
| SCHEMBL18949433 | 0.80 | EGFR (0.56) | EGFRERBB2 | |
| SCHEMBL18949482 | 0.80 | EGFR (0.60) | EGFRERBB2STK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3222620-A1 | CYANOQUINOLINE DERIVATIVES | TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO., LTD. (CN) | 2017-09-27 | — | — | EP | disclosed |