Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1263992 | 0.90 | NPC1 (0.36) | RAB9ANPC1POLBRXFP1LMNA | |
| SCHEMBL1263955 | 0.89 | NPC1 (0.40) | RAB9ANPC1POLBRXFP1PLA2G1B | |
| SCHEMBL1263563 | 0.88 | RXFP1 (0.32) | RAB9ANPC1POLBRXFP1ALDH1A1 | |
| SCHEMBL1263994 | 0.85 | NPC1 (0.52) | RAB9ANPC1POLBLMNAALDH1A1 | |
| SCHEMBL1264010 | 0.81 | NPC1 (0.45) | RAB9ANPC1POLBLMNAALDH1A1 | |
| SCHEMBL1264001 | 0.81 | NPC1 (0.45) | RAB9ANPC1POLBLMNAALDH1A1 | |
| SCHEMBL2814977 | 0.78 | NPC1 (0.45) | RAB9ANPC1POLBLMNAALDH1A1 | |
| SCHEMBL1263990 | 0.78 | NPC1 (0.42) | RAB9ANPC1POLBLMNAALDH1A1 | |
| SCHEMBL1263980 | 0.78 | NPC1 (0.42) | RAB9ANPC1POLBLMNAALDH1A1 | |
| SCHEMBL108807 | 0.74 | NPC1 (0.54) | RAB9ANPC1POLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2332013-A1 | ULTRAVIOLET LIGHT ABSORBING KETONES OF 2-(2-HYDROXYPHENYL) BENZOTRIAZOLE | Chang, Chia-Hu (US) | 2011-06-15 | — | — | EP | claimed |
| WO-2010039229-A1 | ULTRAVIOLET LIGHT ABSORBING KETONES OF 2-(2-HYDROXYPHENYL) BENZOTRIAZOLE | CHANG CHIA-HU (US) | 2010-04-08 | — | — | WO | claimed |