Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.31 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1264001 | 0.86 | NPC1 (0.45) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL4572021 | 0.86 | NPC1 (0.38) | NPC1RAB9ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL1264010 | 0.84 | NPC1 (0.45) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL13370057 | 0.82 | CNR1 (0.38) | NPC1RAB9ALMNAPOLB | |
| SCHEMBL9408718 | 0.82 | NPC1 (0.48) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL9567799 | 0.81 | NPC1 (0.50) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL7574172 | 0.81 | NPC1 (0.50) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL108807 | 0.81 | NPC1 (0.54) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL30893054 | 0.81 | NPC1 (0.50) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL29813370 | 0.81 | NPC1 (0.54) | NPC1RAB9ALMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9404199-B2 | Polyurethane elastic yarn and method for producing same | INVISTA NORTH AMERICA S.A.R.L. (US) | 2016-08-02 | — | — | US | disclosed |
| WO-2013034219-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2013-03-14 | — | — | WO | disclosed |
| EP-2557140-A2 | Liquid-crystalline medium | Merck Patent GmbH (DE) | 2013-02-13 | — | — | EP | disclosed |
| US-20120296016-A1 | POLYURETHANE ELASTIC YARN AND METHOD FOR PRODUCING SAME | TORAY OPELONTEX CO., LTD. (JP) | 2012-11-22 | — | — | US | disclosed |
| EP-2514860-A1 | POLYURETHANE ELASTIC YARN AND METHOD FOR PRODUCING SAME | Toray Opelontex Co., Ltd (JP) | 2012-10-24 | — | — | EP | disclosed |
| EP-2222816-B1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2012-10-17 | — | — | EP | disclosed |
| WO-2012126562-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2012-09-27 | — | — | WO | disclosed |
| EP-2208773-B1 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2012-08-29 | — | — | EP | disclosed |
| WO-2012097858-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2012-07-26 | — | — | WO | disclosed |
| US-20120182200-A1 | COMPONENTS FOR HIGH-FREQUENCY TECHNOLOGY, AND LIQUID-CRYSTALLINE MEDIA | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-07-19 | — | — | US | disclosed |
| WO-2009080261-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2009-07-02 | — | — | WO | disclosed |
| EP-2065361-A2 | Polymerisable compounds | Merck Patent GmbH (DE) | 2009-06-03 | — | — | EP | disclosed |
| WO-2009033564-A2 | ELECTRO-OPTICAL LIGHT CONTROL ELEMENT, ELECTRO-OPTICAL DISPLAY AND CONTROL MEDIUM | MERCK PATENT GMBH (DE) | 2009-03-19 | — | — | WO | disclosed |
| EP-1341871-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2008-10-29 | — | — | EP | disclosed |
| EP-1403356-B1 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2008-09-17 | — | — | EP | disclosed |
| EP-1956069-A1 | Liquid crystalline medium | Merck Patent GmbH (DE) | 2008-08-13 | — | — | EP | disclosed |
| EP-1935963-A1 | Liquid-crystalline medium | Merck Patent GmbH (DE) | 2008-06-25 | — | — | EP | disclosed |
| EP-1932896-A1 | Stilbene derivatives, liquid-crystal mixtures and electro-optical displays | MERCK PATENT GmbH (DE) | 2008-06-18 | — | — | EP | disclosed |
| EP-1447435-B1 | 1,4-Di-(trans-4-Cyclohexyl)benzene derivatives and their use in liquid crystal media and liquid crystal devices | MERCK PATENT GMBH (DE) | 2007-10-24 | — | — | EP | disclosed |
| WO-2007009636-A1 | S-INDACENE AND INDENO[5,6-D][1,3]DIOXOL-DERIVATIVES AND USE THEREOF AS COMPONENTS OF LIQUID-CRYSTAL MIXTURES | MERCK PATENT GMBH (DE) | 2007-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120182200-A1 | COMPONENTS FOR HIGH-FREQUENCY TECHNOLOGY, AND LIQUID-CRYSTALLINE MEDIA | SFRP1, CRY1, MCM3 | NPC1 4293/4885RAB9A 3712/4885LMNA 1098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.