SCHEMBL193907

SCHEMBL193907

C#CCOCCOCCOCCOCCOCCOCCO

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
TSHR P16473 3/20 0.53
MAPK1 P28482 1/20 0.53
THRB P10828 1/20 0.39
HTT P42858 1/20 0.39
MAPT P10636 1/20 0.39
ALDH1A1 P00352 2/20 0.38
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
APP P05067 5/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26845500 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL31503047 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL26845492 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL26845493 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL40248 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL19228951 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL40148 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL40286 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL9511 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL40247 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4543858-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES Draupnir Bio ApS (DK) 2025-04-30 EP disclosed
US-20250002526-A1 PHARMACEUTICAL COMPOSITION HAVING ANTI-CANCER IMMUNOSTIMULATING EFFECT AND/OR IMMUNE CHECKPOINT INHIBITION POTENTIATING EFFECT KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2025-01-02 US disclosed
WO-2023247754-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES DRAUPNIR BIO APS (DK) 2023-12-28 WO disclosed
WO-2023225369-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR CELL-SPECIFIC PHARMACOLOGY DUKE UNIVERSITY (US) 2023-11-23 WO disclosed
US-11753431-B2 Compounds comprising cleavable linker and uses thereof INTOCELL, INC. (KR) 2023-09-12 US disclosed
WO-2023068376-A1 PHARMACEUTICAL COMPOSITION HAVING ANTI-CANCER IMMUNOSTIMULATING EFFECT AND/OR IMMUNE CHECKPOINT INHIBITION POTENTIATING EFFECT 国立大学法人九州大学 2023-04-27 WO disclosed
EP-2400992-B1 METHODS AND COMPOSITIONS FOR PROTEIN LABELLING GENENTECH INC (US) 2015-07-22 EP disclosed
EP-2400992-B1 METHODS AND COMPOSITIONS FOR PROTEIN LABELLING GENENTECH INC (US) 2015-07-22 EP disclosed
US-8865122-B2 Methods and compositions for protein labelling GENENTECH, INC. (US) 2014-10-21 US disclosed
US-8865122-B2 Methods and compositions for protein labelling GENENTECH, INC. (US) 2014-10-21 US disclosed
US-20130216475-A1 METHODS AND COMPOSITIONS FOR PROTEIN LABELLING GENENTECH, INC. (US) 2013-08-22 US disclosed
US-20130216475-A1 METHODS AND COMPOSITIONS FOR PROTEIN LABELLING GENENTECH, INC. (US) 2013-08-22 US disclosed
US-8435488-B2 Methods and compositions for protein labelling GENENTECH, INC. (US) 2013-05-07 US disclosed
US-8435488-B2 Methods and compositions for protein labelling GENENTECH, INC. (US) 2013-05-07 US disclosed
EP-2400992-A1 METHODS AND COMPOSITIONS FOR PROTEIN LABELLING Genentech, Inc. (US) 2012-01-04 EP disclosed
WO-2010099273-A1 METHODS AND COMPOSITIONS FOR PROTEIN LABELLING GENENTECH, INC. (US) 2010-09-02 WO disclosed
WO-2010099273-A1 METHODS AND COMPOSITIONS FOR PROTEIN LABELLING GENENTECH, INC. (US) 2010-09-02 WO disclosed
US-20100221176-A1 METHODS AND COMPOSITIONS FOR PROTEIN LABELLING GENENTECH, INC. 2010-09-02 US disclosed
US-20100221176-A1 METHODS AND COMPOSITIONS FOR PROTEIN LABELLING GENENTECH, INC. 2010-09-02 US disclosed
US-20100221176-A1 METHODS AND COMPOSITIONS FOR PROTEIN LABELLING GENENTECH, INC. 2010-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100221176-A1 METHODS AND COMPOSITIONS FOR PROTEIN LABELLING RAB5IF, RPS27A, PSMA6 MEN1 2279/4885KMT2A 3626/4885TSHR 2895/4885
US-20250002526-A1 PHARMACEUTICAL COMPOSITION HAVING ANTI-CANCER IMMUNOSTIMULATING EFFECT AND/OR IMMUNE CHECKPOINT INHIBITION POTENTIATING EFFECT CD274, PDCD1, PDCD1LG2 MEN1 2631/4885KMT2A 815/4885TSHR 942/4885
US-11753431-B2 Compounds comprising cleavable linker and uses thereof VIP, ANTXR2, TNFRSF9 MEN1 3064/4885KMT2A 3544/4885TSHR 82/4885
US-20130216475-A1 METHODS AND COMPOSITIONS FOR PROTEIN LABELLING RAB5IF, RPS27A, PSMA6 MEN1 2279/4885KMT2A 3626/4885TSHR 2895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.