SCHEMBL40148

SCHEMBL40148

C#CCOCCOCCOCCO

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
TSHR P16473 3/20 0.53
MAPK1 P28482 1/20 0.53
THRB P10828 1/20 0.39
HTT P42858 1/20 0.39
MAPT P10636 1/20 0.39
ALDH1A1 P00352 2/20 0.38
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
APP P05067 5/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26845500 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL31503047 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL26845492 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL26845493 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL40248 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL19228951 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL193907 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL40286 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL9511 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL40247 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024231837-A1 NEW BORON-BASED COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE UNIVERSITA' DEGLI STUDI DI TORINO (IT) 2024-11-14 WO claimed
EP-3886904-B1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-04-22 EP disclosed
WO-2025233682-A1 ANTIBODY DRUG CONJUGATES COMPRISING STING AGONISTS AND USES THEREOF LIGACHEM BIOSCIENCES INC. (KR) 2025-11-13 WO disclosed
US-20250325673-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2025-10-23 US disclosed
US-20250288573-A1 DIMERIC IMMUNO-MODULATORY COMPOUNDS AGAINST CEREBLON-BASED MECHANISMS H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. 2025-09-18 US disclosed
EP-4613773-A2 IRAK DEGRADERS AND USES THEREOF Kymera Therapeutics, Inc. (US) 2025-09-10 EP disclosed
US-20250236633-A1 SYNTHESIS OF ISOMERICALLY PURE POLYOL-BASED PHOSPHORAMIDITES Roche Sequencing Solutions, Inc. (US) 2025-07-24 US disclosed
EP-3731869-B1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2025-07-23 EP disclosed
US-20250163042-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2025-05-22 US disclosed
US-20250129082-A1 N-1 Triazole Substituted Imidazoquinolines, Conjugates Thereof, and Methods SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2025-04-24 US disclosed
US-20110250353-A1 Process for the preparation of a cross-linked multilayer film THE UNIVERSITY OF MELBOURNE (AU) 2011-10-13 US disclosed
US-20110250353-A1 Process for the preparation of a cross-linked multilayer film THE UNIVERSITY OF MELBOURNE (AU) 2011-10-13 US disclosed
US-20110224383-A1 POLY(ETHYLENE GLYCOL) DERIVATIVES FOR METAL-FREE CLICK CHEMISTRY INTEZYNE TECHNOLOGIES, INC. (US) 2011-09-15 US disclosed
US-7947328-B2 Metal pattern forming method FUJIFILM CORPORATION (JP) 2011-05-24 US disclosed
US-7893277-B2 Poly(ethylene glycol) containing chemically disparate endgroups INTEZYNE TECHNOLOGIES, INC. (US) 2011-02-22 US disclosed
US-20100280252-A1 POLY(ETHYLENE GLYCOL) CONTAINING CHEMICALLY DISPARATE ENDGROUPS INTEZYNE TECHNOLOGIES (US) 2010-11-04 US disclosed
US-20100160645-A1 POLY(ETHYLENE GLYCOL) CONTAINING CHEMICALLY DISPARATE ENDGROUPS INTEZYNE TECHNOLOGIES, INC. (US) 2010-06-24 US disclosed
US-7560588-B2 Poly(ethylene glycol) containing chemically disparate endgroups INTEZYNE TECHNOLOGIES, INC. (US) 2009-07-14 US disclosed
US-20090087570-A1 METAL PATTERN FORMING METHOD FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20080207913-A1 Poly(ethylene glycol) containing chemically disparate endgroups INTEZYNE TECHNOLOGIES (US) 2008-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100280252-A1 POLY(ETHYLENE GLYCOL) CONTAINING CHEMICALLY DISPARATE ENDGROUPS GNE, EPRS1, ALG1 MEN1 2092/4885KMT2A 3924/4885TSHR 3867/4885
US-20250325673-A1 IRAK DEGRADERS AND USES THEREOF IRAK2, IRAK3, IRAK1 MEN1 4055/4885KMT2A 445/4885TSHR 3319/4885
US-20100160645-A1 POLY(ETHYLENE GLYCOL) CONTAINING CHEMICALLY DISPARATE ENDGROUPS GNE, EPRS1, ALG1 MEN1 2092/4885KMT2A 3924/4885TSHR 3867/4885
US-20250163042-A1 IRAK DEGRADERS AND USES THEREOF IRAK2, IRAK3, IRAK1 MEN1 4055/4885KMT2A 445/4885TSHR 3319/4885
US-20250288573-A1 DIMERIC IMMUNO-MODULATORY COMPOUNDS AGAINST CEREBLON-BASED MECHANISMS CRBN, CD4, CDR2 MEN1 2337/4885KMT2A 3266/4885TSHR 4105/4885
US-20250129082-A1 N-1 Triazole Substituted Imidazoquinolines, Conjugates Thereof, and Methods IFNG, IFNAR1, IL2 MEN1 707/4885KMT2A 2358/4885TSHR 1515/4885
US-20250236633-A1 SYNTHESIS OF ISOMERICALLY PURE POLYOL-BASED PHOSPHORAMIDITES PARG, PPA1, PGM2 MEN1 947/4885KMT2A 1439/4885TSHR 4736/4885
US-20080207913-A1 Poly(ethylene glycol) containing chemically disparate endgroups GNE, EPRS1, ALG1 MEN1 2092/4885KMT2A 3924/4885TSHR 3867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.