SCHEMBL40286

SCHEMBL40286

C#CCOCCOCCOCCOCCOCCOCCOCCOCCO

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
TSHR P16473 3/20 0.53
MAPK1 P28482 1/20 0.53
THRB P10828 1/20 0.39
HTT P42858 1/20 0.39
MAPT P10636 1/20 0.39
ALDH1A1 P00352 2/20 0.38
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
APP P05067 5/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26845500 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL31503047 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL26845492 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL26845493 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL40248 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL19228951 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL40148 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL193907 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL9511 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL40247 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3729090-B1 MODIFIED BIOTIN-BINDING PROTEINS FOR IMMOBILIZATION PACIFIC BIOSCIENCES CALIFORNIA INC (US) 2026-05-27 EP disclosed
US-20240191287-A1 MODIFIED BIOTIN-BINDING PROTEINS FOR IMMOBILIZATION PACIFIC BIOSCIENCES CALIFORNIA INC (US) 2024-06-13 US disclosed
US-11945838-B2 Method for synthesis of protein amphiphiles INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH (IN) 2024-04-02 US disclosed
US-11781177-B2 Modified biotin-binding proteins for immobilization PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2023-10-10 US disclosed
US-20200199175-A1 METHOD FOR SYNTHESIS OF PROTEIN AMPHIPHILES INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH 2020-06-25 US disclosed
US-10188136-B2 Hydrophobin mimics: process for preparation thereof INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH (IN) 2019-01-29 US disclosed
EP-2590656-B1 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT ARDELYX INC (US) 2017-11-15 EP disclosed
EP-2590656-B1 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT ARDELYX INC (US) 2017-11-15 EP disclosed
US-20170231260-A1 HYDROPHOBIN MIMICS: PROCESS FOR PREPARATION THEREOF INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH (IN) 2017-08-17 US disclosed
US-20170231260-A1 HYDROPHOBIN MIMICS: PROCESS FOR PREPARATION THEREOF INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH (IN) 2017-08-17 US disclosed
US-8916569-B2 Compounds and methods for inhibiting phosphate transport ARDELYX, INC. (US) 2014-12-23 US disclosed
US-8916569-B2 Compounds and methods for inhibiting phosphate transport ARDELYX, INC. (US) 2014-12-23 US disclosed
US-20140023611-A1 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT ARDELYX, INC. 2014-01-23 US disclosed
US-20140023611-A1 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT ARDELYX, INC. 2014-01-23 US disclosed
US-20130336920-A1 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT ARDELYX, INC. (US) 2013-12-19 US disclosed
EP-2590656-A2 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT Ardelyx, Inc. (US) 2013-05-15 EP disclosed
EP-2591354-A1 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT Ardelyx, Inc. (US) 2013-05-15 EP disclosed
WO-2012054110-A2 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT ARDELYX, INC. (US) 2012-04-26 WO disclosed
WO-2012054110-A2 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT ARDELYX, INC. (US) 2012-04-26 WO disclosed
WO-2012006475-A1 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT ARDELYX, INC. (US) 2012-01-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200199175-A1 METHOD FOR SYNTHESIS OF PROTEIN AMPHIPHILES PTMS, VAC14, PDIA6 MEN1 1505/4885KMT2A 3491/4885TSHR 3943/4885
US-20240191287-A1 MODIFIED BIOTIN-BINDING PROTEINS FOR IMMOBILIZATION CACYBP, BTD, HLCS MEN1 3684/4885KMT2A 3073/4885TSHR 3509/4885
US-20170231260-A1 HYDROPHOBIN MIMICS: PROCESS FOR PREPARATION THEREOF CHN2, NEFM, HGF MEN1 317/4885KMT2A 4097/4885TSHR 4020/4885
US-20140023611-A1 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT SLC10A2, SLC34A2, SLC34A3 MEN1 3183/4885KMT2A 4830/4885TSHR 4326/4885
US-20130336920-A1 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT SLC34A2, SLC34A1, SLC10A2 MEN1 2404/4885KMT2A 4695/4885TSHR 3105/4885
US-11945838-B2 Method for synthesis of protein amphiphiles PTMS, VAC14, PDIA6 MEN1 1505/4885KMT2A 3491/4885TSHR 3943/4885
US-11781177-B2 Modified biotin-binding proteins for immobilization CACYBP, BTD, HLCS MEN1 3684/4885KMT2A 3073/4885TSHR 3509/4885
US-10188136-B2 Hydrophobin mimics: process for preparation thereof CHN2, NEFM, HGF MEN1 317/4885KMT2A 4097/4885TSHR 4020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.