Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 10/20 | 0.79 |
| ▸ | DRD2 | P14416 | 3/20 | 0.66 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.66 |
| ▸ | HTR3B | O95264 | 1/20 | 0.66 |
| ▸ | HTR3A | P46098 | 1/20 | 0.66 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.66 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.66 |
| ▸ | ACHE | P22303 | 2/20 | 0.63 |
| ▸ | DRD4 | P21917 | 2/20 | 0.63 |
| ▸ | DRD3 | P35462 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17709611 | 0.91 | HTR4 (0.79) | HTR4DRD2ACHEDRD4DRD3 | |
| SCHEMBL725669 | 0.88 | HTR4 (1.00) | HTR4DRD2HTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL7035321 | 0.87 | HTR4 (0.98) | HTR4DRD2HTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL726793 | 0.87 | HTR4 (0.98) | HTR4DRD2HTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL7388264 | 0.86 | HTR4 (0.73) | HTR4DRD2HTR3EHTR3BHTR3A | |
| SCHEMBL14827434 | 0.85 | HTR4 (0.72) | HTR4DRD2HTR3EHTR3BHTR3A | |
| SCHEMBL14827422 | 0.85 | HTR4 (0.75) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL16403692 | 0.85 | HTR4 (0.72) | HTR4DRD2HTR3EHTR3BHTR3A | |
| SCHEMBL7390082 | 0.85 | HTR4 (0.70) | HTR4 | |
| SCHEMBL2601853 | 0.85 | HTR4 (0.70) | HTR4DRD2HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170275250-A1 | PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE | SK BIOPHARMACEUTICALS CO LTD (KR) | 2017-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170275250-A1 | PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE | PGC, VIP, PIGO | HTR4 308/4885DRD2 126/4885HTR3E 1512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.