Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5493797 | 0.88 | NTRK1 (0.42) | NTRK1MAPTKMT2AMEN1LMNA | |
| SCHEMBL19213536 | 0.86 | EPHX1 (0.46) | NTRK1MAPTKMT2AMEN1ITGB3 | |
| Carbamic Acid SCHEMBL5493402 | 0.84 | NTRK1 (0.40) | NTRK1MAPTKMT2AMEN1LMNA | |
| SCHEMBL5493399 | 0.83 | NTRK1 (0.39) | NTRK1MAPTKMT2AMEN1LMNA | |
| SCHEMBL5492718 | 0.83 | BCHE (0.40) | NTRK1LMNAPOLB | |
| SCHEMBL28755600 | 0.81 | NTRK1 (0.39) | NTRK1MAPTKMT2AMEN1LMNA | |
| Carbamic Acid SCHEMBL5497853 | 0.79 | NTRK1 (0.36) | NTRK1MAPTKMT2AMEN1UTS2R | |
| SCHEMBL5499949 | 0.79 | KMT2A (0.36) | NTRK1MAPTKMT2AMEN1LMNA | |
| SCHEMBL5494715 | 0.79 | ITGB3 (0.36) | NTRK1MAPTKMT2ALMNAITGB3 | |
| SCHEMBL3119092 | 0.79 | LPAR1 (0.38) | NTRK1KMT2AMEN1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170275300-A1 | SYNTHESIS OF CEPHALOSPORIN COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2017-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170275300-A1 | SYNTHESIS OF CEPHALOSPORIN COMPOUNDS | COASY, NRDC, NUCB2 | NTRK1 2913/4885MAPT 4013/4885KMT2A 2284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.