⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL582683 | 1.00 | — | — | |
| SCHEMBL7172665 | 0.76 | GAA (0.39) | — | |
| SCHEMBL23127930 | 0.70 | — | — | |
| SCHEMBL2704673 | 0.68 | GAA (0.41) | — | |
| SCHEMBL331758 | 0.67 | GAA (0.39) | — | |
| SCHEMBL155144 | 0.65 | GAA (0.48) | — | |
| SCHEMBL11286921 | 0.65 | ALDH1A1 (0.44) | — | |
| SCHEMBL3469293 | 0.65 | ALDH1A1 (0.44) | — | |
| SCHEMBL207246 | 0.65 | GAA (0.38) | — | |
| SCHEMBL10648460 | 0.64 | NOX1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2238 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11987588-B2 | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2024-05-21 | — | — | US | claimed |
| WO-2023185986-A1 | BCL-XL INHIBITORS | BEIGENE , LTD. (KY) | 2023-10-05 | — | — | WO | claimed |
| EP-3720858-B1 | MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR USEFUL FOR THE TREATMENT OR PREVENTION OF HEART FAILURE AND DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2023-06-07 | — | — | EP | claimed |
| EP-4149929-A1 | TRIAZINE AND PYRIMIDINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | Bayer Aktiengesellschaft (DE) | 2023-03-22 | — | — | EP | claimed |
| CN-108430972-B | Alpha, beta-unsaturated amide compound | 协和麒麟株式会社 | 2022-12-27 | — | — | CN | claimed |
| US-20220396579-A1 | MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR USEFUL FOR THE TREATMENT OR PREVENTION OF HEART FAILURE AND DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. | 2022-12-15 | — | — | US | claimed |
| US-20220396553-A1 | NOVEL HYDRAZONE DERIVATIVE IN WHICH TERMINAL AMINE GROUP IS SUBSTITUTED WITH ARYL GROUP OR HETEROARYL GROUP, AND USE THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2022-12-15 | — | — | US | claimed |
| US-20220396571-A1 | SPIROPIPERIDINE ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS | MERCK SHARP & DOHME CORP. (US) | 2022-12-15 | — | — | US | claimed |
| CN-113727972-A | Novel hydrazone derivatives in which terminal amino group is substituted with aryl or heteroaryl group, and use thereof | 韩国科学技术研究院 | 2021-11-30 | — | — | CN | claimed |
| WO-2021228734-A1 | TRIAZINE AND PYRIMIDINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2021-11-18 | — | — | WO | claimed |
| EP-0297872-A2 | Novel polymethine dyes and UV absorbers and imaging materials for their use | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-01-04 | — | — | EP | claimed |
| EP-0297871-A2 | Novel polymethine dyes and UV absorbers and imaging materials for their use | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-01-04 | — | — | EP | claimed |
| US-4628061-A | Prostaglandins | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-12-09 | — | — | US | claimed |
| US-4618617-A | ANTIINFLAMMATORY, ANALGESIC AGENTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-10-21 | — | — | US | claimed |
| US-4596823-A | Prostaglandins | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-06-24 | — | — | US | claimed |
| US-4576905-A | Photographically useful chalcogenazoles, chalcogenazolines, and chalcogenazolinium and chalcogenazolium salts | EASTMAN KODAK COMPANY (US) | 1986-03-18 | — | — | US | claimed |
| US-4575483-A | FACILITATE IMAGE FORMATION | EASTMAN KODAK COMPANY (US) | 1986-03-11 | — | — | US | claimed |
| EP-0138362-A2 | Photographic materials containing chalcogenazoles, chalcogenazolines and chalcogenazolinium and chalcogenazolium salts | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-04-24 | — | — | EP | claimed |
| EP-0136847-A2 | Photographically useful chalcogenazolylidene and chalcogenazolium dyes and methods for their preparation | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-04-10 | — | — | EP | claimed |
| US-4113867-A | ANTHELMINTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1978-09-12 | — | — | US | claimed |