Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19401344 | 0.88 | ANO1 (0.38) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL19401343 | 0.85 | KCNH2 (0.39) | L3MBTL1 | |
| SCHEMBL3535937 | 0.83 | KDM4E (0.48) | KDM4EMEN1KMT2AALOX5GAA | |
| SCHEMBL2297483 | 0.79 | PTGS2 (0.50) | KDM4EMEN1KMT2AALOX5GAA | |
| SCHEMBL4791027 | 0.79 | KDM4E (0.47) | KDM4EMEN1KMT2AALOX5GAA | |
| SCHEMBL6119870 | 0.78 | ALOX5 (0.50) | KDM4EMEN1KMT2AALOX5GAA | |
| SCHEMBL4790709 | 0.77 | ALOX5 (0.48) | KDM4EMEN1KMT2AALOX5GAA | |
| SCHEMBL4791020 | 0.77 | MEN1 (0.47) | KDM4EMEN1KMT2AALOX5GAA | |
| SCHEMBL1918070 | 0.77 | MEN1 (0.56) | KDM4EMEN1KMT2AALOX5GAA | |
| SCHEMBL2402438 | 0.76 | MEN1 (0.55) | KDM4EMEN1KMT2AALOX5GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017165233-A1 | BENZOFURAN DERIVATIVES FOR THE TREATMENT OF HEPATITIS C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-28 | — | — | WO | disclosed |