Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL27168864 | 1.00 | KDM4E (0.39) | KDM4ECYP2D6CYP2C19BLMNPSR1 | |
| Sulfuric Acid SCHEMBL18583 | 1.00 | KDM4E (0.39) | KDM4ECYP2D6CYP2C19BLMNPSR1 | |
| Sulfuric Acid SCHEMBL28888125 | 0.97 | KDM4E (0.38) | KDM4ECYP2D6CYP2C19BLMNPSR1 | |
| SCHEMBL27168863 | 0.84 | CA2 (0.30) | — | |
| Methyl Carbamate SCHEMBL31246331 | 0.83 | KDM4E (0.39) | KDM4ECYP2D6CYP2C19BLMNPSR1 | |
| Iodide SCHEMBL6991384 | 0.79 | — | — | |
| Water SCHEMBL27621372 | 0.79 | — | — | |
| SCHEMBL28202086 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL16369776 | 0.79 | — | — | |
| Bromide SCHEMBL28186818 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017384-A1 | AZABENZIMIDAZOLE-BASED COMPOUNDS FOR MODULATING SERINE/THREONINE PROTEIN KINASE FUNCTION | ASTA Medica Aktiengesellschaft (DE) | 2000-07-12 | — | — | EP | claimed |
| WO-1999016438-A1 | AZABENZIMIDAZOLE-BASED COMPOUNDS FOR MODULATING SERINE/THREONINE PROTEIN KINASE FUNCTION | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1999-04-08 | — | — | WO | claimed |
| US-20250228807-A1 | TRANEXAMIC CLASS ARGININE AND HISTIDINE MIMICS AS THERAPEUTIC AGENTS | TRANEXAMIC TECHNOLOGIES, LLC (US) | 2025-07-17 | — | — | US | disclosed |
| WO-2025103367-A1 | LIGAND-DRUG CONJUGATE, LINKER FOR CONJUGATION, AND USE THEREOF | 海南先声再明医药股份有限公司 | 2025-05-22 | — | — | WO | disclosed |
| CN-119486730-A | Tranexamic acid arginine and histidine mimics as therapeutic agents | 传明科技有限责任公司 | 2025-02-18 | — | — | CN | disclosed |
| EP-4499234-A1 | TRANEXAMIC CLASS ARGININE AND HISTIDINE MIMICS AS THERAPEUTIC AGENTS | Tranexamic Technologies, LLC (US) | 2025-02-05 | — | — | EP | disclosed |
| EP-4434982-A1 | (S)-2-(2-METHYLAZETIDIN-1-YL)PYRIMIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | LG Chem, Ltd. (KR) | 2024-09-25 | — | — | EP | disclosed |
| CN-118414332-A | (S) -2- (2-methylazetidin-1-yl) pyrimidine derivatives and pharmaceutical compositions containing the same | 株式会社LG化学 | 2024-07-30 | — | — | CN | disclosed |
| CN-115667244-B | 3-azabicycloalkyl derivatives and pharmaceutical compositions containing the same | 株式会社LG化学 | 2024-04-12 | — | — | CN | disclosed |
| WO-2023192165-A1 | TRANEXAMIC CLASS ARGININE AND HISTIDINE MIMICS AS THERAPEUTIC AGENTS | TRANEXAMIC TECHNOLOGIES, LLC (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2023138601-A1 | BRIDGED RING-SUBSTITUTED HETEROARYL-PYRAN DERIVATIVE, AND USE THEREOF | 南京明德新药研发有限公司 | 2023-07-27 | — | — | WO | disclosed |
| EP-1144390-A2 | KINASE INHIBITORS | Amgen Inc., (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000043373-A2 | KINASE INHIBITORS | AMGEN INC. (US) | 2000-07-27 | — | — | WO | disclosed |
| US-5478946-A | Treating vascular system disorders or cartilage diseases | ABBOTT LABORATORIES (US) | 1995-12-26 | — | — | US | disclosed |
| EP-0296749-A1 | (Substituted aralkyl) heterocyclic compounds | ZENECA LIMITED (GB) | 1988-12-28 | — | — | EP | disclosed |
| US-4790912-A | ELECTROLYTICALLY-GENERATED HYDROGEN AND CATALYST CONVERT METAL SALT IN BATH TO METAL | TECHNO-INSTRUMENTS INVESTMENTS LTD. (IL) | 1988-12-13 | — | — | US | disclosed |
| US-4715894-A | AMINIMIZATION OF SMEAR | TECHNO INSTRUMENTS INVESTMENTS 1983 LTD. (IL) | 1987-12-29 | — | — | US | disclosed |
| US-4657632-A | CONTAINING A THIOUREA AND A UREA COMPOUND | TECHNO INSTRUMENTS INVESTMENTS 1983 LTD. (IL) | 1987-04-14 | — | — | US | disclosed |
| EP-0216531-A1 | Use of immersion tin and tin alloys as a bonding medium for multilayer circuits | TECHNO INSTRUMENTS INVESTMENTS 1983 LTD. (IL) | 1987-04-01 | — | — | EP | disclosed |
| US-3944560-A | BRONCHODILATOR | MERCK & CO., INC. (US) | 1976-03-16 | — | — | US | disclosed |