Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28101497 | 0.88 | HRH2 (0.35) | GNAI3GNAO1GNAI1CHRM2MEN1 | |
| SCHEMBL28112848 | 0.88 | HRH2 (0.35) | GNAI3GNAO1GNAI1CHRM2MEN1 | |
| SCHEMBL7512749 | 0.80 | GNAI3 (0.33) | GNAI3GNAO1GNAI1 | |
| SCHEMBL11612677 | 0.80 | ALDH1A1 (0.41) | CHRM2MEN1CYP2D6KMT2ACHRM1 | |
| SCHEMBL7587454 | 0.80 | CHRM2 (0.34) | CHRM2MEN1CYP2D6KMT2ACHRM1 | |
| SCHEMBL8483160 | 0.79 | SMN1; SMN2 (0.50) | MEN1KMT2ACHRM1 | |
| SCHEMBL27637917 | 0.79 | GNAI3 (0.34) | GNAI3GNAO1GNAI1CHRM2CHRM1 | |
| SCHEMBL31591139 | 0.78 | ALDH1A1 (0.37) | CHRM2MEN1CYP2D6KMT2ACHRM1 | |
| SCHEMBL29052233 | 0.78 | ALDH1A1 (0.37) | CHRM2MEN1CYP2D6KMT2ACHRM1 | |
| SCHEMBL7216698 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323587-A | Small molecules for autoimmune diseases and cancer treatment | 阿索斯治疗公司 | 2023-06-23 | — | — | CN | disclosed |
| US-20110172126-A1 | LIBRARIES OF PEPTIDE CONJUGATES AND METHODS FOR MAKING THEM | XENOME LTD (AU) | 2011-07-14 | — | — | US | disclosed |
| EP-2331561-A1 | LIBRARIES OF PEPTIDE CONJUGATES AND METHODS FOR MAKING THEM | Xenome Ltd (AU) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010025510-A1 | LIBRARIES OF PEPTIDE CONJUGATES AND METHODS FOR MAKING THEM | XENOME LTD (AU) | 2010-03-11 | — | — | WO | disclosed |