Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.50 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3351989 | 0.92 | CASP2 (0.56) | FAAHMCL1CASP2CNR1NAAA | |
| SCHEMBL19703760 | 0.91 | FAAH (0.65) | FAAHMCL1CASP2CNR1NAAA | |
| SCHEMBL28327787 | 0.89 | FAAH (0.76) | FAAHCASP2CNR1NAAADNM1 | |
| SCHEMBL5909462 | 0.87 | FAAH (0.64) | FAAHMCL1CASP2NAAAMMP1 | |
| Hexadecanoic Acid Propylamide SCHEMBL16393833 | 0.85 | FAAH (0.84) | FAAHCASP2CNR1NAAADNM1 | |
| SCHEMBL840681 | 0.84 | — | — | |
| SCHEMBL10124173 | 0.83 | PHF8 (0.52) | FAAHMCL1CASP2CNR1NAAA | |
| SCHEMBL9921404 | 0.83 | CASP2 (0.48) | FAAHMCL1CASP2CNR1NAAA | |
| SCHEMBL17860105 | 0.83 | KMT2A (0.58) | FAAHMCL1CASP2NAAAKMT2A | |
| SCHEMBL17740222 | 0.83 | CASP2 (0.48) | FAAHMCL1CASP2CNR1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3432934-B1 | PRODRUGS OF CYTOTOXIC AGENTS WITH ENZYMATICALLY CLEAVABLE GROUPS | Bayer Pharma AG (DE) | 2022-02-23 | — | — | EP | disclosed |
| WO-2017162663-A1 | PRODRUGS OF CYTOTOXIC ACTIVE AGENTS HAVING ENZYMATICALLY CLEAVABLE GROUPS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-28 | — | — | WO | disclosed |