Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD1 | O95696 | 10/20 | 0.66 |
| ▸ | BRPF1 | P55201 | 10/20 | 0.66 |
| ▸ | TAF1 | P21675 | 9/20 | 0.66 |
| ▸ | BRD4 | O60885 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19404616 | 0.96 | BRD1 (0.66) | BRD1BRPF1TAF1BRD4MEN1 | |
| SCHEMBL19404857 | 0.86 | BRD1 (0.77) | BRD1BRPF1TAF1BRD4MEN1 | |
| SCHEMBL19404521 | 0.80 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4MEN1 | |
| SCHEMBL19404625 | 0.77 | BRD1 (0.77) | BRD1BRPF1TAF1BRD4MEN1 | |
| SCHEMBL16773474 | 0.76 | MEN1 (0.64) | BRD1BRPF1TAF1MEN1KMT2A | |
| SCHEMBL19404459 | 0.76 | BRD1 (0.73) | BRD1BRPF1TAF1BRD4MEN1 | |
| SCHEMBL19404455 | 0.75 | BRD1 (0.74) | BRD1BRPF1TAF1BRD4MEN1 | |
| SCHEMBL16784368 | 0.75 | MEN1 (0.68) | BRD1BRPF1TAF1BRD4MEN1 | |
| SCHEMBL19405041 | 0.75 | BRD1 (0.67) | BRD1BRPF1TAF1BRD4MEN1 | |
| SCHEMBL19404516 | 0.75 | TAF1 (0.59) | BRD1BRPF1TAF1BRD4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017162661-A1 | 1H-BENZO[DE]ISOQUINOLINE-1,3(2H)-DIONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-28 | — | — | WO | disclosed |