Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD1 | O95696 | 17/20 | 0.55 |
| ▸ | TAF1 | P21675 | 16/20 | 0.51 |
| ▸ | BRPF1 | P55201 | 16/20 | 0.51 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.51 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.51 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.51 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 3/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19404850 | 0.86 | BRD1 (0.70) | BRD1TAF1BRPF1TAF1LCREBBP | |
| SCHEMBL19405052 | 0.85 | TAF1 (0.61) | BRD1TAF1BRPF1TAF1LCREBBP | |
| SCHEMBL19404626 | 0.82 | BRD1 (0.73) | BRD1TAF1BRPF1TAF1LCREBBP | |
| SCHEMBL19405050 | 0.77 | BRD1 (0.55) | BRD1TAF1BRPF1TAF1LCREBBP | |
| SCHEMBL19404622 | 0.77 | BRD1 (0.73) | BRD1TAF1BRPF1BRD4 | |
| SCHEMBL19404433 | 0.76 | BRD1 (0.69) | BRD1TAF1BRPF1TAF1LCREBBP | |
| SCHEMBL19405011 | 0.76 | BRD1 (0.69) | BRD1TAF1BRPF1TAF1LCREBBP | |
| SCHEMBL19404498 | 0.76 | BRD1 (0.69) | BRD1TAF1BRPF1TAF1LCREBBP | |
| SCHEMBL19404448 | 0.76 | BRD1 (0.74) | BRD1TAF1BRPF1BRD4 | |
| SCHEMBL19404604 | 0.75 | BRD1 (0.58) | BRD1TAF1BRPF1TAF1LCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017162661-A1 | 1H-BENZO[DE]ISOQUINOLINE-1,3(2H)-DIONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-28 | — | — | WO | disclosed |