Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.81 |
| ▸ | TLR9 | Q9NR96 | 16/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NSD2 | O96028 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19405196 | 0.90 | TLR7 (1.00) | TLR7TLR9 | |
| SCHEMBL19406427 | 0.89 | TLR7 (0.80) | TLR7TLR9 | |
| SCHEMBL19406135 | 0.83 | TLR9 (0.75) | TLR7TLR9 | |
| SCHEMBL19385008 | 0.80 | TLR9 (0.64) | TLR7TLR9SMN1; SMN2NSD2 | |
| SCHEMBL29936661 | 0.80 | TLR9 (0.64) | TLR7TLR9SMN1; SMN2NSD2 | |
| SCHEMBL19385104 | 0.80 | TLR9 (0.69) | TLR7TLR9SMN1; SMN2NSD2 | |
| SCHEMBL19385134 | 0.80 | TLR7 (1.00) | TLR7TLR9 | |
| SCHEMBL29936638 | 0.80 | TLR7 (1.00) | TLR7TLR9 | |
| SCHEMBL19405144 | 0.80 | TLR7 (0.90) | TLR7TLR9SMN1; SMN2NSD2 | |
| SCHEMBL19385168 | 0.79 | TLR7 (1.00) | TLR7TLR9SMN1; SMN2NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017163264-A1 | BLOCKING TOLL-LIKE RECEPTOR 9 SIGNALING WITH SMALL MOLECULE ANTAGONIST | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-09-28 | — | — | WO | disclosed |