Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MMP9 | P14780 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 16/20 | 0.34 |
| ▸ | CA2 | P00918 | 16/20 | 0.34 |
| ▸ | CA9 | Q16790 | 15/20 | 0.34 |
| ▸ | CA12 | O43570 | 5/20 | 0.33 |
| ▸ | CA7 | P43166 | 5/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.33 |
| ▸ | CA3 | P07451 | 4/20 | 0.33 |
| ▸ | CA4 | P22748 | 4/20 | 0.33 |
| ▸ | CA6 | P23280 | 4/20 | 0.33 |
| ▸ | CA5A | P35218 | 4/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19405342 | 1.00 | ALDH1A1 (0.62) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL8914005 | 0.98 | TSHR (0.60) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL21595681 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL26247047 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL26247045 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL18746519 | 0.83 | KDM4E (0.62) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL6484412 | 0.83 | LMNA (0.68) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL18419074 | 0.81 | LMNA (0.65) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL11400795 | 0.81 | LMNA (0.65) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL8860696 | 0.81 | LMNA (0.65) | ALDH1A1TSHRKDM4EUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3225614-B1 | KINETIC RESOLUTION OF ASYMMETRIC CATALYTIC HYDROGENATION OF RACEMIC -HYDROXY ESTER AND APPLICATION THEREOF | ZHEJIANG JIUZHOU PHARM CO LTD (CN) | 2020-10-28 | — | — | EP | disclosed |
| US-10676422-B2 | Kinetic resolution of racemic hydroxy ester via asymmetric catalytic hydrogenation and application thereof | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2020-06-09 | — | — | US | disclosed |
| US-20170334831-A1 | Kinetic resolution of racemic hydroxy ester via asymmetric catalytic hydrogenation and application thereof | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2017-11-23 | — | — | US | disclosed |
| EP-3225614-A1 | KINETIC RESOLUTION OF ASYMMETRIC CATALYTIC HYDROGENATION OF RACEMIC -HYDROXY ESTER AND APPLICATION THEREOF | Zhejiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2017-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10676422-B2 | Kinetic resolution of racemic hydroxy ester via asymmetric catalytic hydrogenation and application thereof | CYP8B1, HRH4, CYP3A5 | ALDH1A1 2665/4885TSHR 2420/4885KDM4E 1086/4885 |
| US-20170334831-A1 | Kinetic resolution of racemic hydroxy ester via asymmetric catalytic hydrogenation and application thereof | CYP8B1, CYP3A5, HRH4 | ALDH1A1 2416/4885TSHR 1854/4885KDM4E 1057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.