Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 15/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2039599 | 1.00 | FFAR2 (0.59) | FFAR2LMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL29787736 | 1.00 | FFAR2 (0.59) | FFAR2LMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL2039602 | 1.00 | FFAR2 (0.59) | FFAR2LMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL23658499 | 0.81 | LMNA (0.53) | LMNAMAPTSMN1; SMN2HTTTSHR | |
| SCHEMBL2040215 | 0.77 | LMNA (0.66) | LMNAMAPTSMN1; SMN2HTTTSHR | |
| SCHEMBL29787531 | 0.77 | FFAR2 (0.71) | FFAR2 | |
| SCHEMBL2038056 | 0.77 | FFAR2 (0.71) | FFAR2 | |
| SCHEMBL29787712 | 0.76 | FFAR2 (0.80) | FFAR2 | |
| SCHEMBL2037572 | 0.76 | FFAR2 (0.80) | FFAR2 | |
| SCHEMBL29787855 | 0.75 | FFAR2 (0.75) | FFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513053-B1 | Pyrrolidine carboxylic acid derivatives as agonists of G-protein coupled receptor 43 (GPR43), pharmaceutical composition and methods for use in treating metabolic disorders | OGEDA SA (BE) | 2017-10-04 | — | — | EP | disclosed |