Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 10/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TNF | P01375 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19377138 | 0.93 | ABCB1 (0.45) | ABCB1ACACBSMN1; SMN2NOD1KMT2A | |
| SCHEMBL19377139 | 0.93 | ABCB1 (0.45) | ABCB1ACACBSMN1; SMN2NOD1KMT2A | |
| SCHEMBL24800429 | 0.89 | ROCK2 (0.43) | ACACBKMT2AHTTMEN1CYP2D6 | |
| SCHEMBL19377012 | 0.83 | ACACB (0.39) | ABCB1ACACBSMN1; SMN2NOD1KMT2A | |
| SCHEMBL19377013 | 0.83 | ACACB (0.39) | ABCB1ACACBSMN1; SMN2NOD1KMT2A | |
| SCHEMBL19377057 | 0.83 | KCNA1 (0.38) | ACACBSMN1; SMN2KMT2AHTTLMNA | |
| SCHEMBL19398904 | 0.82 | MLNR (0.45) | CYP2D6 | |
| SCHEMBL19377340 | 0.82 | ROCK2 (0.43) | ACACBSMN1; SMN2NOD1KMT2AHTT | |
| SCHEMBL19377186 | 0.82 | ROCK2 (0.43) | ACACBSMN1; SMN2NOD1KMT2AHTT | |
| SCHEMBL19377185 | 0.82 | ROCK2 (0.43) | ACACBSMN1; SMN2NOD1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017162390-A1 | BENZENESULFONYL-ASYMMETRIC UREAS AND MEDICAL USES THEREOF | HELSINN HEALTHCARE SA (CH) | 2017-09-28 | — | — | WO | disclosed |