Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 12/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18481784 | 0.85 | ELANE (0.50) | ELANEALDH1A1LMNACYP3A4HIF1A | |
| SCHEMBL28203282 | 0.83 | ELANE (0.59) | ELANETSHR | |
| SCHEMBL1790848 | 0.83 | TSHR (0.53) | TSHRALDH1A1LMNAKDM4EL3MBTL1 | |
| SCHEMBL1791401 | 0.82 | TSHR (0.52) | ELANETSHRALDH1A1LMNAHIF1A | |
| SCHEMBL5837459 | 0.81 | TSHR (0.50) | TSHRALDH1A1LMNAKDM4EL3MBTL1 | |
| SCHEMBL6838437 | 0.81 | TSHR (0.50) | TSHRALDH1A1LMNAKDM4EL3MBTL1 | |
| SCHEMBL22020868 | 0.81 | ELANE (0.56) | ELANELMNA | |
| SCHEMBL23318138 | 0.79 | TSHR (0.49) | ELANETSHRALDH1A1LMNAKDM4E | |
| SCHEMBL10529200 | 0.79 | TSHR (0.49) | TSHRALDH1A1LMNAKDM4EL3MBTL1 | |
| Fenobucarb SCHEMBL73674 | 0.78 | ALDH1A1 (0.58) | TSHRALDH1A1LMNAKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11643657-B2 | Chiral control | WAVE LIFE SCIENCES LTD. (SG) | 2023-05-09 | — | — | US | disclosed |
| US-20210130821-A1 | CHIRAL CONTROL | WAVE LIFE SCIENCES LTD. (SG) | 2021-05-06 | — | — | US | disclosed |
| US-10590413-B2 | Chiral control | WAVE LIFE SCIENCES LTD. (SG) | 2020-03-17 | — | — | US | disclosed |
| US-20170275621-A1 | CHIRAL CONTROL | WAVE LIFE SCIENCES USA, INC. | 2017-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210130821-A1 | CHIRAL CONTROL | RNGTT, POLI, NSUN3 | ELANE 2181/4885TSHR 3259/4885ALDH1A1 2867/4885 |
| US-20170275621-A1 | CHIRAL CONTROL | RNGTT, POLI, NSUN3 | ELANE 2181/4885TSHR 3259/4885ALDH1A1 2867/4885 |
| US-11643657-B2 | Chiral control | RNGTT, POLI, NSUN3 | ELANE 2181/4885TSHR 3259/4885ALDH1A1 2867/4885 |
| US-10590413-B2 | Chiral control | RNGTT, POLI, NSUN3 | ELANE 2181/4885TSHR 3259/4885ALDH1A1 2867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.