⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19409218 | 0.77 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL20385415 | 0.74 | — | — | |
| SCHEMBL19409234 | 0.74 | ALDH1A1 (0.50) | — | |
| SCHEMBL5371464 | 0.73 | — | — | |
| SCHEMBL19409257 | 0.72 | ADORA2A (0.41) | — | |
| SCHEMBL5490092 | 0.70 | — | — | |
| SCHEMBL18256648 | 0.70 | YTHDC1 (0.40) | — | |
| SCHEMBL12084898 | 0.69 | — | — | |
| SCHEMBL26348127 | 0.68 | ADORA2A (0.32) | — | |
| SCHEMBL19409243 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170281501-A1 | 4,5-DIAMINOIMIDAZOLES AS NOVEL DEVELOPER-TYPE OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2017-10-05 | — | — | US | claimed |
| US-12018032-B2 | Crystalline forms of N-[4-[4-(4-morpholinyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl]-4-[[3(r)-[(1-oxo-2-propen-1-yl)amino]-1-piperidinyl]methyl]-2-pyridinecarboxamide as an irreversible inhibitor of menin-MLL interaction | BIOMEA FUSION, INC. (US) | 2024-06-25 | — | — | US | disclosed |
| US-20170281501-A1 | 4,5-DIAMINOIMIDAZOLES AS NOVEL DEVELOPER-TYPE OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2017-10-05 | — | — | US | disclosed |
| US-20170281501-A1 | 4,5-DIAMINOIMIDAZOLES AS NOVEL DEVELOPER-TYPE OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2017-10-05 | — | — | US | disclosed |
| US-20170281501-A1 | 4,5-DIAMINOIMIDAZOLES AS NOVEL DEVELOPER-TYPE OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2017-10-05 | — | — | US | disclosed |