Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1258412 | 0.82 | CA9 (0.42) | CA9CA12CA1CA2TSHR | |
| SCHEMBL17273886 | 0.79 | OGA (0.30) | — | |
| SCHEMBL17472194 | 0.79 | OGA (0.30) | — | |
| SCHEMBL15258387 | 0.77 | CA9 (0.46) | CA9CA12CA1CA2TSHR | |
| SCHEMBL1259563 | 0.76 | CA9 (0.42) | CA9CA12CA1CA2TSHR | |
| SCHEMBL11249103 | 0.75 | CA9 (0.49) | CA9CA12CA1CA2TSHR | |
| SCHEMBL26759992 | 0.75 | PDPK1 (0.36) | TSHR | |
| SCHEMBL17265253 | 0.74 | — | — | |
| SCHEMBL17266924 | 0.74 | OGA (0.37) | CA9CA12CA1CA2 | |
| SCHEMBL23563178 | 0.73 | CA9 (0.51) | CA9CA12CA1CA2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3357931-B1 | METHODS OF SYNTHESIS OF TRITERPENE PROSAPOGENINS AND TRITERPENE SAPONINS | SLOAN KETTERING INST CANCER RES (US) | 2020-07-22 | — | — | EP | disclosed |
| EP-3357931-A1 | METHODS OF SYNTHESIS OF TRITERPENE PROSAPOGENINS AND TRITERPENE SAPONINS | Sloan Kettering Institute For Cancer Research (US) | 2018-08-08 | — | — | EP | disclosed |
| EP-2280987-B1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS, AND USES THEREOF | SLOAN KETTERING INST CANCER RES (US) | 2018-05-23 | — | — | EP | disclosed |
| US-20170283450-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF | MEMORIAL SLOAN-KETTERING INST FOR CANCER RES (US) | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170283450-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF | LSS, CYP51A1, TLR7 | CA9 3028/4885CA12 1541/4885CA1 1970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.