Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | XDH | P47989 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3960092 | 0.89 | PTGER4 (0.43) | KDM4EPTGER4POLBALDH1A1KMT2A | |
| SCHEMBL1943217 | 0.85 | PTGER4 (0.44) | KDM4EPTGER4TLR7LMNATDP1 | |
| SCHEMBL1942259 | 0.81 | PTGER4 (0.35) | KDM4EPTGER4TLR7LMNATDP1 | |
| SCHEMBL1943031 | 0.78 | LMNA (0.46) | KDM4EPTGER4TLR7GAALMNA | |
| SCHEMBL1941310 | 0.74 | KDM4E (0.36) | KDM4EPTGER4TLR7LMNAALDH1A1 | |
| SCHEMBL29832637 | 0.69 | LMNA (0.46) | KDM4EGAAPOLBLMNAXDH | |
| SCHEMBL28582556 | 0.69 | LMNA (0.46) | KDM4EGAAPOLBLMNAXDH | |
| SCHEMBL1942913 | 0.69 | GLP1R (0.45) | KDM4EPTGER4GAALMNAALDH1A1 | |
| SCHEMBL2362229 | 0.68 | KDM4E (0.58) | KDM4EPTGER4TLR7GAAALDH1A1 | |
| SCHEMBL11374354 | 0.67 | KDM4E (0.81) | KDM4EPTGER4GAAPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466166-B2 | Benzimidazole derivatives as selective acid pump inhibitors | RAQUALIA PHARMA INC. (JP) | 2013-06-18 | — | — | US | disclosed |
| EP-2081939-B1 | BENZIMIDAZOLE DERIVATIVES AS SELECTIVE ACID PUMP INHIBITORS | RAQUALIA PHARMA INC (JP) | 2011-06-15 | — | — | EP | disclosed |
| US-20100048532-A1 | Benzimidazole Derivatives as Selective Acid Pump Inhibitors | RAQUALIA PHARMA INC. (JP) | 2010-02-25 | — | — | US | disclosed |
| EP-2081939-A1 | BENZIMIDAZOLE DERIVATIVES AS SELECTIVE ACID PUMP INHIBITORS | RaQualia Pharma Inc (JP) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008035195-A1 | BENZIMIDAZOLE DERIVATIVES AS SELECTIVE ACID PUMP INHIBITORS | RAQUALIA PHARMA INC. (JP) | 2008-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048532-A1 | Benzimidazole Derivatives as Selective Acid Pump Inhibitors | HRH2, HRH4, HRH1 | KDM4E 4217/4885PTGER4 39/4885TLR7 2369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.