Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 14/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1940964 | 0.89 | KDM4E (0.49) | PTGER4KDM4EBRD4ALDH1A1MEN1 | |
| SCHEMBL1943217 | 0.86 | PTGER4 (0.44) | PTGER4HCAR3KDM4EBRD4ALDH1A1 | |
| SCHEMBL1942259 | 0.82 | PTGER4 (0.35) | PTGER4KDM4EBRD4ALDH1A1 | |
| SCHEMBL1942913 | 0.79 | GLP1R (0.45) | PTGER4KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5598194 | 0.77 | PTGER4 (0.41) | PTGER4HCAR3 | |
| SCHEMBL5598558 | 0.76 | PPARA (0.43) | PTGER4ALDH1A1 | |
| SCHEMBL1943031 | 0.70 | LMNA (0.46) | PTGER4KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1940860 | 0.69 | BRD4 (0.45) | PTGER4KDM4EBRD4ALDH1A1MEN1 | |
| SCHEMBL28950510 | 0.69 | CA12 (0.47) | KDM4EALDH1A1MEN1THRBKMT2A | |
| SCHEMBL1942633 | 0.68 | PTGER4 (0.35) | PTGER4KDM4EBRD4ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081939-A1 | BENZIMIDAZOLE DERIVATIVES AS SELECTIVE ACID PUMP INHIBITORS | RaQualia Pharma Inc (JP) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008035195-A1 | BENZIMIDAZOLE DERIVATIVES AS SELECTIVE ACID PUMP INHIBITORS | RAQUALIA PHARMA INC. (JP) | 2008-03-27 | — | — | WO | disclosed |