Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.31 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.30 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17131356 | 0.89 | STING1 (0.30) | STING1 | |
| SCHEMBL19412686 | 0.85 | SLC28A1 (0.32) | STING1SLC28A1SLC28A2 | |
| SCHEMBL19412766 | 0.84 | SLC28A1 (0.32) | STING1SLC28A1SLC28A2 | |
| SCHEMBL17106691 | 0.82 | — | — | |
| SCHEMBL17106779 | 0.82 | SLC28A1 (0.30) | SLC28A1SLC28A2 | |
| SCHEMBL17131357 | 0.76 | STING1 (0.30) | STING1 | |
| SCHEMBL19412768 | 0.75 | SLC28A1 (0.30) | SLC28A1SLC28A2 | |
| SCHEMBL17131355 | 0.75 | — | — | |
| SCHEMBL17131349 | 0.74 | POLRMT (0.35) | — | |
| SCHEMBL24941676 | 0.74 | POLRMT (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9777035-B2 | 4′-substituted nucleoside reverse transcriptase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-10-03 | — | — | US | disclosed |