Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23555007 | 0.89 | L3MBTL1 (0.56) | L3MBTL1KDM4EGLAGAAPKM | |
| SCHEMBL10192197 | 0.80 | L3MBTL1 (0.50) | L3MBTL1KDM4EGLAGAAPKM | |
| SCHEMBL31030375 | 0.79 | L3MBTL1 (0.49) | L3MBTL1KDM4EGLAGAAPKM | |
| SCHEMBL178417 | 0.79 | L3MBTL1 (0.49) | L3MBTL1KDM4EGLAGAAPKM | |
| SCHEMBL27479781 | 0.78 | L3MBTL1 (0.49) | L3MBTL1KDM4EGLAGAAPKM | |
| SCHEMBL8347805 | 0.78 | L3MBTL1 (0.49) | L3MBTL1KDM4EGLAGAAPKM | |
| SCHEMBL4277869 | 0.77 | L3MBTL1 (0.47) | L3MBTL1KDM4EGLAGAAPKM | |
| SCHEMBL10218755 | 0.75 | L3MBTL1 (0.46) | L3MBTL1KDM4EGLAGAAPKM | |
| SCHEMBL4438706 | 0.75 | KDM4E (0.47) | L3MBTL1KDM4EGLAGAAPKM | |
| SCHEMBL7132578 | 0.75 | L3MBTL1 (0.44) | L3MBTL1KDM4EGLAGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9777018-B2 | Compounds as modulators of GPR-119 | RHIZEN PHARMACEUTICALS SA (CH) | 2017-10-03 | — | — | US | disclosed |