Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 12/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.34 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19044569 | 0.90 | MEN1 (0.37) | MAP4K4CSNK1G2CLK4MKNK2MAP4K5 | |
| SCHEMBL19053761 | 0.77 | MAP4K4 (0.38) | SIRT2MAOAMAOBHSD17B1HSD17B2 | |
| SCHEMBL19413710 | 0.75 | SIRT2 (0.37) | SIRT2MAOAMAOBHSD17B1HSD17B2 | |
| SCHEMBL20894863 | 0.70 | SIRT2 (0.51) | SIRT2HSD17B1HSD17B2CTRC | |
| SCHEMBL24353250 | 0.69 | HSD17B1 (0.59) | SIRT2HSD17B1HSD17B2 | |
| SCHEMBL21667606 | 0.69 | HSD17B1 (0.59) | SIRT2HSD17B1HSD17B2 | |
| SCHEMBL21667461 | 0.69 | HSD17B1 (0.59) | SIRT2HSD17B1HSD17B2 | |
| SCHEMBL22186308 | 0.69 | HSD17B1 (0.59) | SIRT2HSD17B1HSD17B2 | |
| SCHEMBL24888973 | 0.68 | PAX8 (0.44) | MAOAMAOBHSD17B1HSD17B2CTRC | |
| SCHEMBL18731737 | 0.67 | MEN1 (0.61) | HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9780310-B2 | Heterocyclic compound for organic electroluminescent device and its application | TOSOH CORPORATION (JP) | 2017-10-03 | — | — | US | disclosed |