Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GSR | P00390 | 9/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15909979 | 0.91 | KDM4E (0.43) | KDM4EALDH1A1SMN1; SMN2HPGDGLA | |
| SCHEMBL15909985 | 0.86 | KDM4E (0.40) | KDM4EALDH1A1SMN1; SMN2HPGDGLA | |
| SCHEMBL16476450 | 0.85 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2HPGDGLA | |
| SCHEMBL27033894 | 0.84 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2HPGDGLA | |
| SCHEMBL16476446 | 0.82 | KDM4E (0.43) | KDM4EALDH1A1SMN1; SMN2HPGDGLA | |
| Iodide SCHEMBL17254512 | 0.81 | KDM4E (0.43) | KDM4EALDH1A1SMN1; SMN2HPGDGLA | |
| SCHEMBL16476452 | 0.81 | KDM4E (0.42) | KDM4EMAPTMEN1USP2KMT2A | |
| SCHEMBL14399199 | 0.80 | SMN1; SMN2 (0.58) | KDM4EALDH1A1SMN1; SMN2HPGDGLA | |
| SCHEMBL15901239 | 0.79 | MEN1 (0.67) | KDM4EALDH1A1SMN1; SMN2HPGDGLA | |
| SCHEMBL13965818 | 0.79 | KDM4E (0.38) | KDM4EALDH1A1SMN1; SMN2HPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3225112-A1 | PHOTOSENSITISER DISPERSION AND USE OF THE SAME | Universitätsklinikum Regensburg (DE) | 2017-10-04 | — | — | EP | disclosed |