Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GSR | P00390 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HSF1 | Q00613 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | GALK1 | P51570 | 3/20 | 0.42 |
| ▸ | BLM | P54132 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30387533 | 0.87 | TDP2 (0.45) | KDM4ESMN1; SMN2ALDH1A1GSRMAPT | |
| SCHEMBL16476446 | 0.84 | KDM4E (0.43) | KDM4ESMN1; SMN2ALDH1A1GLAHPGD | |
| SCHEMBL19415772 | 0.84 | KDM4E (0.43) | KDM4ESMN1; SMN2ALDH1A1GLAHPGD | |
| SCHEMBL14399199 | 0.84 | SMN1; SMN2 (0.58) | KDM4ESMN1; SMN2ALDH1A1GLAHPGD | |
| Iodide SCHEMBL17254512 | 0.83 | KDM4E (0.43) | KDM4ESMN1; SMN2ALDH1A1GLAHPGD | |
| SCHEMBL864708 | 0.80 | KDM4E (0.43) | KDM4ESMN1; SMN2ALDH1A1GLAHPGD | |
| SCHEMBL16479714 | 0.78 | KDM4E (0.46) | KDM4ESMN1; SMN2ALDH1A1GLAHPGD | |
| SCHEMBL11307834 | 0.78 | SMN1; SMN2 (0.48) | KDM4ESMN1; SMN2ALDH1A1GLAHPGD | |
| SCHEMBL864002 | 0.77 | MAPT (0.44) | KDM4ESMN1; SMN2ALDH1A1GLAHPGD | |
| SCHEMBL14335594 | 0.77 | CYP1A2 (0.48) | KDM4ESMN1; SMN2ALDH1A1GLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250188117-A1 | C-Terminal Peptide Modification | TECHNISCHE UNIVERSITEIT DELFT (NL) | 2025-06-12 | — | — | US | disclosed |
| US-20240199686-A1 | C-Terminal Peptide Modification | TECHNISCHE UNIVERSITEIT DELFT (NL) | 2024-06-20 | — | — | US | disclosed |
| EP-4314007-A1 | C-TERMINAL PEPTIDE MODIFICATION | Technische Universiteit Delft (NL) | 2024-02-07 | — | — | EP | disclosed |
| EP-4308582-A1 | C-TERMINAL PEPTIDE MODIFICATION | Technische Universiteit Delft (NL) | 2024-01-24 | — | — | EP | disclosed |
| CN-117062825-A | C-terminal peptide modification | 代尔夫特科技大学 | 2023-11-14 | — | — | CN | disclosed |
| CN-117015550-A | C-terminal peptide modification | 代尔夫特科技大学 | 2023-11-07 | — | — | CN | disclosed |
| WO-2022203512-A1 | C-TERMINAL PEPTIDE MODIFICATION | TECHNISCHE UNIVERSITEIT DELFT (NL) | 2022-09-29 | — | — | WO | disclosed |
| WO-2022197184-A1 | C-TERMINAL PEPTIDE MODIFICATION | TECHNISCHE UNIVERSITEIT DELFT (NL) | 2022-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199686-A1 | C-Terminal Peptide Modification | PTMS, NGLY1, QPCT | KDM4E 3889/4885SMN1; SMN2 3989/4885ALDH1A1 4186/4885 |
| US-20250188117-A1 | C-Terminal Peptide Modification | PTMS, NGLY1, QPCT | KDM4E 4074/4885SMN1; SMN2 3782/4885ALDH1A1 3987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.