Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 16/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19416414 | 0.83 | ENPP2 (0.35) | TLR8TLR7 | |
| SCHEMBL18772013 | 0.81 | TLR8 (0.42) | TLR8TLR7 | |
| SCHEMBL1590055 | 0.81 | TLR8 (0.60) | TLR8TLR7 | |
| SCHEMBL19416290 | 0.80 | TLR8 (0.38) | TLR8TLR7 | |
| SCHEMBL18772079 | 0.79 | TLR8 (0.41) | TLR8TLR7 | |
| SCHEMBL18771975 | 0.79 | TLR8 (0.45) | TLR8TLR7 | |
| SCHEMBL19416470 | 0.79 | TLR8 (0.41) | TLR8TLR7 | |
| SCHEMBL18771743 | 0.78 | TLR8 (0.43) | TLR8TLR7 | |
| SCHEMBL19416294 | 0.78 | TLR8 (0.37) | TLR8TLR7 | |
| SCHEMBL19416398 | 0.78 | TLR8 (0.41) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3225623-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | Ventirx Pharmaceuticals, Inc. (US) | 2017-10-04 | — | — | EP | disclosed |