Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRF1 | P14222 | 9/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19416531 | 0.94 | — | — | |
| SCHEMBL19416285 | 0.89 | — | — | |
| SCHEMBL19416434 | 0.84 | PRF1 (0.31) | PRF1KDM4EMAPT | |
| SCHEMBL19416343 | 0.81 | — | — | |
| SCHEMBL19416391 | 0.80 | — | — | |
| SCHEMBL18771991 | 0.80 | TLR8 (0.33) | — | |
| SCHEMBL19416383 | 0.80 | TLR8 (0.37) | — | |
| SCHEMBL18772157 | 0.80 | TLR8 (0.32) | KDM4E | |
| SCHEMBL18772155 | 0.79 | TLR8 (0.34) | — | |
| SCHEMBL19416337 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3225623-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | Ventirx Pharmaceuticals, Inc. (US) | 2017-10-04 | — | — | EP | disclosed |