Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18830089 | 0.84 | MET (0.39) | METKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL31364861 | 0.73 | CLK1 (0.38) | MET | |
| SCHEMBL31364948 | 0.73 | MET (0.36) | MET | |
| SCHEMBL31531609 | 0.73 | CLK1 (0.38) | MET | |
| SCHEMBL31364793 | 0.72 | CCR4 (0.45) | MET | |
| SCHEMBL31364985 | 0.72 | MET (0.42) | METKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL16022043 | 0.72 | MET (0.45) | METKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL15146081 | 0.67 | MAPK6 (0.56) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL18181670 | 0.65 | KCNN4 (0.41) | METKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL16012245 | 0.65 | MAPK6 (0.41) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2807161-B1 | TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2017-10-04 | — | — | EP | disclosed |