Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | CLK1 | P49759 | 2/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19416674 | 0.84 | MET (0.36) | METALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6203819 | 0.79 | ALDH1A1 (0.36) | CYP1A2CYP2C19ALDH1A1SMN1; SMN2DYRK1A | |
| SCHEMBL31364861 | 0.78 | CLK1 (0.38) | METDYRK1AATMCLK1 | |
| SCHEMBL31531609 | 0.78 | CLK1 (0.38) | METDYRK1AATMCLK1 | |
| SCHEMBL31364948 | 0.78 | MET (0.36) | METDYRK1AATMCLK1 | |
| SCHEMBL31364793 | 0.77 | CCR4 (0.45) | MET | |
| SCHEMBL31364985 | 0.77 | MET (0.42) | METCYP1A2CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL23507945 | 0.77 | ALDH1A1 (0.34) | CYP1A2CYP2C19ALDH1A1SMN1; SMN2DYRK1A | |
| SCHEMBL16022043 | 0.77 | MET (0.45) | METALDH1A1SMN1; SMN2DYRK1AATM | |
| SCHEMBL20251286 | 0.74 | ALDH1A1 (0.33) | CYP1A2CYP2C19ALDH1A1SMN1; SMN2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964649-B1 | TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF DISEASES SUCH AS CANCER | MERCK PATENT GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |