Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955903 | 0.85 | RAB9A (0.43) | RAB9AMEN1KMT2APOLBMAPT | |
| SCHEMBL12270174 | 0.82 | LMNA (0.52) | RAB9AMEN1KMT2APOLBMAPT | |
| SCHEMBL16954256 | 0.81 | RAB9A (0.38) | RAB9AMEN1KMT2APDE4APDE4B | |
| SCHEMBL16953515 | 0.81 | RAB9A (0.40) | RAB9AMEN1KMT2APOLBMAPT | |
| SCHEMBL8296526 | 0.79 | CYP2C9 (0.61) | MEN1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL31556000 | 0.79 | CA12 (0.65) | RAB9AMEN1KMT2ATSHRCA1 | |
| SCHEMBL13889423 | 0.79 | CA12 (0.65) | RAB9AMEN1KMT2ATSHRCA1 | |
| SCHEMBL13895732 | 0.77 | MAPK1 (0.59) | RAB9AMEN1KMT2APDE4APDE4B | |
| SCHEMBL30842512 | 0.77 | MAPT (0.58) | RAB9AMEN1KMT2AMAPTTSHR | |
| SCHEMBL18212635 | 0.77 | MAPT (0.58) | RAB9AMEN1KMT2AMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3097097-B1 | IMIDAZOLES FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | HOFFMANN LA ROCHE (CH) | 2017-10-04 | — | — | EP | disclosed |