Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.77 |
| ▸ | MEN1 | O00255 | 10/20 | 0.77 |
| ▸ | MAPT | P10636 | 10/20 | 0.77 |
| ▸ | RECQL | P46063 | 5/20 | 0.77 |
| ▸ | RAB9A | P51151 | 5/20 | 0.77 |
| ▸ | THRB | P10828 | 4/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.77 |
| ▸ | NPC1 | O15118 | 3/20 | 0.77 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | DUSP22 | Q9NRW4 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14680223 | 0.87 | MEN1 (1.00) | KMT2AMEN1MAPTRECQLRAB9A | |
| SCHEMBL15761667 | 0.75 | HSPD1 (0.71) | KMT2AMEN1MAPTRAB9AMAPK1 | |
| SCHEMBL13873081 | 0.73 | KMT2A (0.50) | KMT2AMEN1MAPTRECQLRAB9A | |
| SCHEMBL6282463 | 0.73 | KMT2A (1.00) | KMT2AMEN1MAPTRECQLRAB9A | |
| SCHEMBL3895249 | 0.73 | KMT2A (1.00) | KMT2AMEN1MAPTRECQLRAB9A | |
| SCHEMBL3895245 | 0.73 | KMT2A (1.00) | KMT2AMEN1MAPTRECQLRAB9A | |
| SCHEMBL12637255 | 0.72 | DUSP22 (0.65) | KMT2AMEN1MAPTRAB9AMAPK1 | |
| SCHEMBL12637129 | 0.72 | DUSP22 (0.80) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL12637123 | 0.71 | CFTR (0.74) | KMT2AMEN1MAPTRAB9AALDH1A1 | |
| SCHEMBL11595445 | 0.70 | KMT2A (0.56) | KMT2AMEN1MAPTRAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170281649-A1 | COMPOUNDS AND THERAPEUTIC USES | UNITY BIOTECHNOLOGY, INC. | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170281649-A1 | COMPOUNDS AND THERAPEUTIC USES | TP53, NQO1, SHMT2 | KMT2A 3471/4885MEN1 3416/4885MAPT 1762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.